Caspase 1 抗体 (Cleaved-Asp210)
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- 抗原 See all Caspase 1 (CASP1) 抗体
- Caspase 1 (CASP1)
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抗原表位
- Cleaved-Asp210
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适用
- 人
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宿主
- 兔
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克隆类型
- 多克隆
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标记
- This Caspase 1 antibody is un-conjugated
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应用范围
- Western Blotting (WB), ELISA, Immunohistochemistry (Paraffin-embedded Sections) (IHC (p)), Immunofluorescence (IF)
- 产品特性
- Polyclonal Antibody
- 纯化方法
- Affinity purification
- 免疫原
- Synthesized peptide derived from the Internal region of human Caspase-1
- 亚型
- IgG
- Top Product
- Discover our top product CASP1 Primary Antibody
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- 应用备注
- WB 1:500-2000, IHC 1:50-300, IF 1:50-300
- 限制
- 仅限研究用
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- 状态
- Liquid
- 浓度
- 1 mg/mL
- 缓冲液
- PBS with 0.02 % sodium azide, 0.5 % BSA and 50 % glycerol, pH 7.4
- 储存液
- Sodium azide
- 注意事项
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
- 储存条件
- -20 °C
- 储存方法
- Store at -20°C. Avoid freeze / thaw cycles.
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- 抗原
- Caspase 1 (CASP1)
- 别名
- CASP1 (CASP1 产品)
- 背景
- Thiol protease that cleaves IL-1 beta between an Asp and an Ala, releasing the mature cytokine which is involved in a variety of inflammatory processes. Important for defense against pathogens. Cleaves and activates sterol regulatory element binding proteins (SREBPs). Can also promote apoptosis.
- 分子量
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Observed_MW: 25 kDa
Calculated_MW: 45 kDa
- UniProt
- P29466
- 途径
- Apoptosis, Interferon-gamma Pathway, Positive Regulation of Endopeptidase Activity, Inflammasome
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