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ERK1/2 抗体 (pTyr205, pTyr222)

MAPK1/3 适用: 人, 小鼠, 大鼠 IHC (p) 宿主: 小鼠 Monoclonal 4D4 unconjugated
产品编号 ABIN7250980
发货至: 中国
  • 抗原 See all ERK1/2 (MAPK1/3) 抗体
    ERK1/2 (MAPK1/3) (Mitogen-Activated Protein Kinase 1/3 (MAPK1/3))
    抗原表位
    • 45
    • 38
    • 30
    • 30
    • 16
    • 11
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    pTyr205, pTyr222
    适用
    • 186
    • 154
    • 151
    • 23
    • 22
    • 18
    • 7
    • 3
    • 2
    • 2
    • 2
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    人, 小鼠, 大鼠
    宿主
    • 138
    • 49
    • 4
    小鼠
    克隆类型
    • 135
    • 56
    单克隆
    标记
    • 90
    • 12
    • 8
    • 5
    • 5
    • 5
    • 5
    • 5
    • 5
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    • 5
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    • 3
    • 3
    • 3
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    • 1
    • 1
    This ERK1/2 antibody is un-conjugated
    应用范围
    • 150
    • 65
    • 51
    • 49
    • 48
    • 38
    • 22
    • 22
    • 20
    • 13
    • 4
    • 4
    • 3
    Immunohistochemistry (Paraffin-embedded Sections) (IHC (p))
    产品特性
    Phosphorylated antibody
    纯化方法
    Protein A purification
    免疫原
    Synthetic Peptide of Phospho-ERK 1/2 (Tyr222/205)
    克隆位点
    4D4
    亚型
    IgG
    Top Product
    Discover our top product MAPK1/3 Primary Antibody
  • 应用备注
    IHC 1:100-200
    限制
    仅限研究用
  • 状态
    Liquid
    浓度
    1 mg/mL
    缓冲液
    PBS with 0.02 % sodium azide, 0.5 % BSA and 50 % glycerol, pH 7.4
    储存液
    Sodium azide
    注意事项
    This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
    储存条件
    -20 °C
    储存方法
    Store at -20°C. Avoid freeze / thaw cycles.
  • 抗原
    ERK1/2 (MAPK1/3) (Mitogen-Activated Protein Kinase 1/3 (MAPK1/3))
    别名
    ERK 1/2 (MAPK1/3 产品)
    别名
    erk1/2 antibody, mitogen-activated protein kinase antibody, erk1/2 antibody
    背景
    Involved in both the initiation and regulation of meiosis, mitosis, and postmitotic functions in differentiated cells by phosphorylating a number of transcription factors such as ELK1. Phosphorylates EIF4EBP1, required for initiation of translation. Phosphorylates microtubule-associated protein 2 (MAP2). Phosphorylates SPZ1 (By similarity). Phosphorylates heat shock factor protein 4 (HSF4) and ARHGEF2.Acts as a transcriptional repressor. Binds to a [GC]AAA[GC] consensus sequence. Repress the expression of interferon gamma-induced genes. Seems to bind to the promoter of CCL5, DMP1, IFIH1, IFITM1, IRF7, IRF9, LAMP3, OAS1, OAS2, OAS3 and STAT1. Transcriptional activity is independent of kinase activity.
    UniProt
    P27361, P28482
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