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NFKBIB 抗体
NFKBIB
适用: 人, 小鼠, 大鼠
IHC (p), IF
宿主: 小鼠
Monoclonal
unconjugated
NFKBIB抗体详情
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抗原
See all NFKBIB 抗体
NFKBIB
(NF-kappa-B inhibitor beta (NFKBIB))
适用
All reactivities for NFKBIB 抗体
人, 小鼠, 大鼠
宿主
All hosts for NFKBIB 抗体
小鼠
克隆类型
All clonalities for NFKBIB 抗体
单克隆
标记
All conjugates for NFKBIB 抗体
This NFKBIB antibody is un-conjugated
应用范围
All applications for NFKBIB 抗体
Immunohistochemistry (Paraffin-embedded Sections) (IHC (p)), Immunofluorescence (IF)
产品特性
Monoclonal Antibody
纯化方法
Protein A purification
免疫原
Recombinant Protein
亚型
IgG
Top Product
Discover our top product NFKBIB Primary Antibody
Alternatives
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使用细节
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应用备注
IHC 1:200, IF 1:50-200
限制
仅限研究用
贮存及处理
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状态
Liquid
浓度
1 mg/mL
缓冲液
PBS with 0.02 % sodium azide, 0.5 % BSA and 50 % glycerol, pH 7.4
储存液
Sodium azide
注意事项
This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
储存条件
-20 °C
储存方法
Store at -20°C. Avoid freeze / thaw cycles.
NFKBIB目标详情
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抗原
NFKBIB
(NF-kappa-B inhibitor beta (NFKBIB))
别名
NFKBIB (NFKBIB 产品 )
别名
NFKBIB antibody, IKB-beta antibody, IKappaBbeta antibody, IkB antibody, IkBb antibody, IKBB antibody, TRIP9 antibody, NFKB inhibitor beta antibody, nuclear factor of kappa light polypeptide gene enhancer in B cells inhibitor, beta antibody, NFKBIB antibody, Nfkbib antibody
背景
Inhibits NF-kappa-B by complexing with and trapping it in the cytoplasm. However, the unphosphorylated form resynthesized after cell stimulation is able to bind NF-kappa-B allowing its transport to the nucleus and protecting it to further NFKBIA-dependent inactivation. Association with inhibitor kappa B-interacting NKIRAS1 and NKIRAS2 prevent its phosphorylation rendering it more resistant to degradation, explaining its slower degradation.
UniProt
Q15653
途径
NF-kappaB Signaling , Activation of Innate immune Response , Maintenance of Protein Location , Toll-Like Receptors Cascades
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