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NBR1 抗体

NBR1 适用: 人, 小鼠, 大鼠 IF, IHC (p) 宿主: 小鼠 Monoclonal 4C6 unconjugated
产品编号 ABIN7250371
发货至: 中国
  • 抗原 See all NBR1 抗体
    NBR1 (Neighbor of BRCA1 Gene 1 (NBR1))
    适用
    • 19
    • 7
    • 5
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    人, 小鼠, 大鼠
    宿主
    • 14
    • 7
    小鼠
    克隆类型
    • 17
    • 4
    单克隆
    标记
    • 21
    This NBR1 antibody is un-conjugated
    应用范围
    • 18
    • 9
    • 6
    • 3
    • 3
    • 2
    • 1
    Immunofluorescence (IF), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p))
    产品特性
    Monoclonal Antibody
    纯化方法
    Protein A purification
    免疫原
    Recombinant Protein of NBR1
    克隆位点
    4C6
    亚型
    IgG
    Top Product
    Discover our top product NBR1 Primary Antibody
  • 应用备注
    IHC 1:50-300, IF 1:50-1:200
    限制
    仅限研究用
  • 状态
    Liquid
    浓度
    1 mg/mL
    缓冲液
    PBS with 0.02 % sodium azide and 50 % glycerol pH 7.4.
    储存液
    Sodium azide
    注意事项
    This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
    储存条件
    -20 °C
    储存方法
    Store at -20°C. Avoid freeze / thaw cycles.
  • 抗原
    NBR1 (Neighbor of BRCA1 Gene 1 (NBR1))
    别名
    NBR1 (NBR1 产品)
    背景
    The protein encoded by this gene was originally identified as an ovarian tumor antigen monitored in ovarian cancer. The encoded protein contains a B-box/coiled-coil motif, which is present in many genes with transformation potential. It functions as a specific autophagy receptor for the selective autophagic degradation of peroxisomes by forming intracellular inclusions with ubiquitylated autophagic substrates. This gene is located on a region of chromosome 17q21.1 that is in close proximity to the BRCA1 tumor suppressor gene. Alternative splicing of this gene results in multiple transcript variants.NBR1 (NBR1, Autophagy Cargo Receptor) is a Protein Coding gene. Diseases associated with NBR1 include Inclusion Body Myositis and Synucleinopathy. Among its related pathways are Mitophagy - animal. GO annotations related to this gene include ubiquitin binding and mitogen-activated protein kinase binding.
    UniProt
    Q14596
    途径
    Autophagy
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