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KIF7 抗体

KIF7 适用: 人, 大鼠, 小鼠 IHC (p), IF 宿主: 小鼠 Monoclonal 3I4 unconjugated
产品编号 ABIN7250092
发货至: 中国
  • 抗原 See all KIF7 抗体
    KIF7 (Kinesin Family Member 7 (KIF7))
    适用
    • 24
    • 15
    • 15
    • 2
    • 2
    • 2
    • 1
    人, 大鼠, 小鼠
    宿主
    • 20
    • 4
    小鼠
    克隆类型
    • 20
    • 4
    单克隆
    标记
    • 13
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    This KIF7 antibody is un-conjugated
    应用范围
    • 12
    • 10
    • 3
    • 3
    • 2
    • 2
    • 1
    Immunohistochemistry (Paraffin-embedded Sections) (IHC (p)), Immunofluorescence (IF)
    产品特性
    Monoclonal Antibody
    纯化方法
    Protein A purification
    免疫原
    Synthetic Peptide
    克隆位点
    3I4
    亚型
    IgG
  • 应用备注
    IHC 1:100-1:300, IF 1:50-200
    限制
    仅限研究用
  • 状态
    Liquid
    浓度
    1 mg/mL
    缓冲液
    PBS with 0.02 % sodium azide and 50 % glycerol pH 7.4.
    储存液
    Sodium azide
    注意事项
    This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
    储存条件
    -20 °C
    储存方法
    Store at -20°C. Avoid freeze / thaw cycles.
  • 抗原
    KIF7 (Kinesin Family Member 7 (KIF7))
    别名
    KIF7 (KIF7 产品)
    别名
    KIF7 antibody, DDBDRAFT_0204609 antibody, DDBDRAFT_0206583 antibody, DDB_0204609 antibody, DDB_0206583 antibody, ACLS antibody, HLS2 antibody, JBTS12 antibody, UNQ340 antibody, cos2 antibody, costal2 antibody, kinesin family member 7 antibody, KIF7 antibody, kif7 antibody, Kif7 antibody
    背景
    This gene encodes a cilia-associated protein belonging to the kinesin family. This protein plays a role in the sonic hedgehog (SHH) signaling pathway through the regulation of GLI transcription factors. It functions as a negative regulator of the SHH pathway by preventing inappropriate activation of GLI2 in the absence of ligand, and as a positive regulator by preventing the processing of GLI3 into its repressor form. Mutations in this gene have been associated with various ciliopathies.KIF7 (Kinesin Family Member 7) is a Protein Coding gene. Diseases associated with KIF7 include Acrocallosal Syndrome and Hydrolethalus Syndrome 2. Among its related pathways are Signaling by Hedgehog and Signaling by GPCR. GO annotations related to this gene include ATPase activity and microtubule motor activity. An important paralog of this gene is KIF27.
    UniProt
    Q2M1P5
    途径
    Hedgehog Signaling
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