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ALPL 抗体

ALPL 适用: 人, 小鼠, 大鼠 WB 宿主: 兔 Polyclonal unconjugated
产品编号 ABIN7250008
发货至: 中国
  • 抗原 See all ALPL 抗体
    ALPL (Alkaline Phosphatase, Liver/bone/kidney (ALPL))
    适用
    • 81
    • 48
    • 16
    • 5
    • 1
    • 1
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    • 1
    • 1
    人, 小鼠, 大鼠
    宿主
    • 78
    • 19
    • 1
    • 1
    克隆类型
    • 81
    • 18
    多克隆
    标记
    • 56
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    • 4
    • 2
    • 2
    • 2
    • 1
    • 1
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    • 1
    • 1
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    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
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    This ALPL antibody is un-conjugated
    应用范围
    • 65
    • 38
    • 27
    • 15
    • 13
    • 13
    • 11
    • 11
    • 8
    • 6
    • 5
    • 3
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    Western Blotting (WB)
    产品特性
    Polyclonal Antibody
    纯化方法
    Affinity purification
    免疫原
    Recombinant protein corresponding to Mouse Alkaline Phosphatase
    亚型
    IgG
    Top Product
    Discover our top product ALPL Primary Antibody
  • 应用备注
    WB 1:500-1:2000
    限制
    仅限研究用
  • 状态
    Liquid
    浓度
    200 μg/mL
    缓冲液
    PBS with 0.02 % sodium azide, 1 % BSA and 50 % glycerol, pH 7.4
    储存液
    Sodium azide
    注意事项
    This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
    储存条件
    -20 °C
    储存方法
    Store at -20°C. Avoid freeze / thaw cycles.
  • 抗原
    ALPL (Alkaline Phosphatase, Liver/bone/kidney (ALPL))
    别名
    ALPL (ALPL 产品)
    别名
    ALP antibody, iap antibody, alpl antibody, AP-TNAP antibody, APTNAP antibody, HOPS antibody, TNAP antibody, TNSALP antibody, Akp-2 antibody, Akp2 antibody, PHOA antibody, TNS-AP antibody, alkaline phosphatase, liver/bone/kidney L homeolog antibody, alkaline phosphatase, liver/bone/kidney antibody, alkaline phosphatase, intestinal, gene 2 antibody, alkaline phosphatase, liver/bone/kidney pseudogene antibody, alpl.L antibody, ALPL antibody, alpi.2 antibody, LOC100031702 antibody, Alpl antibody
    背景
    There are at least four distinct but related alkaline phosphatases: intestinal, placental, placental-like, and liver/bone/kidney (tissue non-specific). The first three are located together on chromosome 2, while the tissue non-specific form is located on chromosome 1. The product of this gene is a membrane bound glycosylated enzyme that is not expressed in any particular tissue and is, therefore, referred to as the tissue-nonspecific form of the enzyme. The exact physiological function of the alkaline phosphatases is not known. A proposed function of this form of the enzyme is matrix mineralization, however, mice that lack a functional form of this enzyme show normal skeletal development. This enzyme has been linked directly to hypophosphatasia, a disorder that is characterized by hypercalcemia and includes skeletal defects. The character of this disorder can vary, however, depending on the specific mutation since this determines age of onset and severity of symptoms. Alternatively spliced transcript variants have been described.
    分子量

    Observed_MW: 55 kDa

    Calculated_MW: 57 kDa

    UniProt
    P05186, P09242, P08289
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