Laminin beta 1 抗体
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- 抗原 See all Laminin beta 1 (LAMB1) 抗体
- Laminin beta 1 (LAMB1) (Laminin, beta 1 (LAMB1))
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适用
- 小鼠, 大鼠
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宿主
- 兔
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克隆类型
- 多克隆
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标记
- This Laminin beta 1 antibody is un-conjugated
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应用范围
- Western Blotting (WB)
- 产品特性
- Polyclonal Antibody
- 纯化方法
- Affinity purification
- 免疫原
- Recombinant protein corresponding to Mouse Laminin beta1
- 亚型
- IgG
- Top Product
- Discover our top product LAMB1 Primary Antibody
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- 应用备注
- WB 1:500-1:2000
- 限制
- 仅限研究用
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- 状态
- Liquid
- 浓度
- 1.2 mg/mL
- 缓冲液
- PBS with 0.02 % sodium azide, 1 % BSA and 50 % glycerol, pH 7.4
- 储存液
- Sodium azide
- 注意事项
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
- 储存条件
- -20 °C
- 储存方法
- Store at -20°C. Avoid freeze / thaw cycles.
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- 抗原
- Laminin beta 1 (LAMB1) (Laminin, beta 1 (LAMB1))
- 别名
- Laminin beta1 (LAMB1 产品)
- 别名
- CLM antibody, LIS5 antibody, fc20b05 antibody, gup antibody, lamb1 antibody, sb:cb95 antibody, wu:fc20b05 antibody, Lamb1-1 antibody, LAMB1 antibody, C77966 antibody, C80098 antibody, C81607 antibody, D130003D08Rik antibody, Lamb-1 antibody, laminin subunit beta 1 antibody, laminin, beta 1a antibody, laminin B1 antibody, LAMB1 antibody, lamb1a antibody, Lamb1 antibody, lamb1 antibody
- 背景
- Laminins, a family of extracellular matrix glycoproteins, are the major noncollagenous constituent of basement membranes. They have been implicated in a wide variety of biological processes including cell adhesion, differentiation, migration, signaling, neurite outgrowth and metastasis. Laminins are composed of 3 non identical chains: laminin alpha, beta and gamma (formerly A, B1, and B2, respectively) and they form a cruciform structure consisting of 3 short arms, each formed by a different chain, and a long arm composed of all 3 chains. Each laminin chain is a multidomain protein encoded by a distinct gene. Several isoforms of each chain have been described. This gene encodes the beta chain isoform laminin, beta 1. The beta 1 chain has 7 structurally distinct domains which it shares with other beta chain isomers. The C-terminal helical region containing domains I and II are separated by domain alpha, domains III and V contain several EGF-like repeats, and domains IV and VI have a globular conformation. Laminin, beta 1 is expressed in most tissues that produce basement membranes, and is one of the 3 chains constituting laminin 1, the first laminin isolated from Engelbreth-Holm-Swarm (EHS) tumor. A sequence in the beta 1 chain that is involved in cell attachment, chemotaxis, and binding to the laminin receptor was identified and shown to have the capacity to inhibit metastasis.
- 分子量
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Observed_MW: 220 kDa
Calculated_MW: 198 kDa
- UniProt
- P07942, P02469
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