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FAS 抗体

FAS 适用: 人, 小鼠 IHC 宿主: 小鼠 Monoclonal 10E5B10 unconjugated
产品编号 ABIN7249652
发货至: 中国
  • 抗原 See all FAS 抗体
    FAS (TNF Receptor Superfamily, Member 6 (FAS))
    适用
    • 214
    • 62
    • 58
    • 19
    • 5
    • 4
    • 4
    • 2
    • 1
    • 1
    人, 小鼠
    宿主
    • 159
    • 88
    • 4
    • 2
    • 2
    • 1
    • 1
    小鼠
    克隆类型
    • 156
    • 99
    • 1
    单克隆
    标记
    • 116
    • 26
    • 26
    • 13
    • 11
    • 7
    • 3
    • 3
    • 3
    • 3
    • 3
    • 3
    • 3
    • 3
    • 3
    • 3
    • 3
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    This FAS antibody is un-conjugated
    应用范围
    • 159
    • 117
    • 74
    • 56
    • 35
    • 34
    • 28
    • 26
    • 26
    • 20
    • 17
    • 9
    • 8
    • 5
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    • 4
    • 2
    • 2
    • 2
    • 2
    • 1
    • 1
    Immunohistochemistry (IHC)
    产品特性
    Monoclonal Antibody
    纯化方法
    Affinity purification
    免疫原
    KLH conjugated Synthetic peptide corresponding to Mouse FAS
    克隆位点
    10E5B10
    亚型
    IgG
    Top Product
    Discover our top product FAS Primary Antibody
  • 应用备注
    IHC 1:200-1:800
    限制
    仅限研究用
  • 状态
    Liquid
    浓度
    420 μg/mL
    缓冲液
    PBS with 0.02 % sodium azide, 1 % BSA and 50 % glycerol, pH 7.4
    储存液
    Sodium azide
    注意事项
    This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
    储存条件
    -20 °C
    储存方法
    Store at -20°C. Avoid freeze / thaw cycles.
  • 抗原
    FAS (TNF Receptor Superfamily, Member 6 (FAS))
    别名
    FAS (FAS 产品)
    背景
    FAS,also named as CD95,APO-1,APT1,FAS1 and TNFRSF6,is a receptor for TNFSF6/FASLG. It is a cell surface receptor belonging to the TNF receptor superfamily,can mediates apoptosis by ligation with an agonistic anti-Fas antibody or Fas ligand. Stimulation of Fas results in the aggregation of its intracellular death domains,leading to the formation of the death-inducing signaling complex (DISC). FAS-mediated apoptosis may have a role in the induction of peripheral tolerance,in the antigen-stimulated suicide of mature T-cells,or both. The secreted isoforms 2 to 6 block apoptosis (in vitro). This anti-Fas monoclonal antibody can be used to induce apoptosis in cell cultures through Fas by imitating the Fas-ligand.
    UniProt
    P25445, P25446
    途径
    p53 Pathway, Apoptosis, Production of Molecular Mediator of Immune Response, Positive Regulation of Endopeptidase Activity
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