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ALKBH8 抗体

ALKBH8 适用: 人 WB, ELISA, IHC 宿主: 兔 Polyclonal unconjugated
产品编号 ABIN7249214
发货至: 中国
  • 抗原 See all ALKBH8 抗体
    ALKBH8 (AlkB, Alkylation Repair Homolog 8 (ALKBH8))
    适用
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    宿主
    • 34
    克隆类型
    • 34
    多克隆
    标记
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    This ALKBH8 antibody is un-conjugated
    应用范围
    • 13
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    Western Blotting (WB), ELISA, Immunohistochemistry (IHC)
    产品特性
    Polyclonal Antibody
    纯化方法
    Antigen affinity purification
    免疫原
    Full length fusion protein
    亚型
    IgG
    Top Product
    Discover our top product ALKBH8 Primary Antibody
  • 应用备注
    WB 1:500-1:2000, IHC 1:25-1:100, ELISA 1:5000-1:10000
    限制
    仅限研究用
  • 状态
    Liquid
    浓度
    0.6 mg/mL
    缓冲液
    PBS with 0.05 % Sodium azide and 40 % Glycerol, pH 7.4
    储存液
    Sodium azide
    注意事项
    This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
    储存条件
    -20 °C
    储存方法
    Store at -20°C. Avoid freeze / thaw cycles.
  • 抗原
    ALKBH8 (AlkB, Alkylation Repair Homolog 8 (ALKBH8))
    别名
    ALKBH8 (ALKBH8 产品)
    别名
    ABH8 antibody, 4930562C03Rik antibody, 8030431D03Rik antibody, 9430088N01Rik antibody, Abh8 antibody, alkB homolog 8, tRNA methyltransferase antibody, ALKBH8 antibody, Alkbh8 antibody
    背景
    ALKBH8 (alkylated DNA repair protein AlkB homolog 8) is a 664 amino acid protein that is encoded by a gene located on chromosome 11. ALKBH8 contains one RRM (RNA recognition motif) domain and belongs to the AlkB family of proteins. ALKBH8 is one of many homologs of the Escherichia coli protein AlkB. AlkB functions to protect DNA and RNA against damage from environmental methylating compounds by directly reversing 1-methyladenine (1-meA) and 3-methylcytosine (3-meC) cytotoxic alkylation lesions in DNA and RNA. The enzyme acts by oxidative demethylation, utilizing ferrous iron and alpha-ketoglutarate as cofactors, 2-oxoglutarate as a co-substrate and molecular oxygen as the oxidizing agent. Three isoforms exist for ALKBH8 due alternative splicing of the gene.
    分子量

    Observed_MW: Refer to figures

    Calculated_MW: 75 kDa

    UniProt
    Q96BT7
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