DOK3 抗体
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- 抗原 See all DOK3 抗体
- DOK3 (Docking Protein 3 (DOK3))
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适用
- 人
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宿主
- 兔
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克隆类型
- 多克隆
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标记
- This DOK3 antibody is un-conjugated
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应用范围
- Western Blotting (WB), ELISA
- 产品特性
- Polyclonal Antibody
- 纯化方法
- Antigen affinity purification
- 免疫原
- Fusion protein of human DOK3
- 亚型
- IgG
- Top Product
- Discover our top product DOK3 Primary Antibody
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- 应用备注
- WB 1:500-1:2000, ELISA 1:1000-1:5000
- 限制
- 仅限研究用
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- 状态
- Liquid
- 浓度
- 0.4 mg/mL
- 缓冲液
- PBS with 0.05 % Sodium azide and 40 % Glycerol, pH 7.4
- 储存液
- Sodium azide
- 注意事项
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
- 储存条件
- -20 °C
- 储存方法
- Store at -20°C. Avoid freeze / thaw cycles.
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- 抗原
- DOK3 (Docking Protein 3 (DOK3))
- 别名
- DOK3 (DOK3 产品)
- 别名
- DOK3 antibody, DOKL antibody, AI450713 antibody, Dokl antibody, docking protein 3 antibody, DOK3 antibody, Dok3 antibody
- 背景
- DOK3 gene maps to chromosome 5q35.3. Dok3 was tyrosine phosphorylated by Src family members Lck, Fyn, and Lyn. Immunoprecipitation studies showed that Dok3 bound inhibitors SHIP and Csk but did not bind RasGAP. Dok3 binding to SHIP occurred via the SH2 domain. Dok3 also bound Csk via the Csk SH2 domain with possible involvement of the Csk SH3 domain as well.DOK proteins are enzymatically inert adaptor or scaffolding proteins. They provide a docking platform for the assembly of multimolecular signaling complexes. DOK3 is a negative regulator of JNK signaling in B-cells through interaction with INPP5D/SHIP1. May modulate ABL1 function
- 分子量
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Observed_MW: Refer to figures
Calculated_MW: 53 kDa
- UniProt
- Q7L591
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