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IRG1 抗体

IRG1 适用: 人, 小鼠 ELISA, WB 宿主: 兔 Polyclonal unconjugated
产品编号 ABIN7248602
发货至: 中国
  • 抗原 See all IRG1 products
    IRG1 (Immunoresponsive Gene 1 (IRG1))
    适用
    人, 小鼠
    宿主
    • 12
    克隆类型
    • 12
    多克隆
    标记
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    This IRG1 antibody is un-conjugated
    应用范围
    • 5
    • 1
    • 1
    • 1
    • 1
    ELISA, Western Blotting (WB)
    产品特性
    Polyclonal Antibody
    纯化方法
    Antigen affinity purification
    免疫原
    Synthetic peptide of human ACOD1
    亚型
    IgG
  • 应用备注
    WB 1:500-1:2000, ELISA 1:5000-1:10000
    限制
    仅限研究用
  • 状态
    Liquid
    浓度
    1.32 mg/mL
    缓冲液
    PBS with 0.05 % Sodium azide and 40 % Glycerol, pH 7.4
    储存液
    Sodium azide
    注意事项
    This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
    储存条件
    -20 °C
    储存方法
    Store at -20°C. Avoid freeze / thaw cycles.
  • 抗原
    IRG1 (Immunoresponsive Gene 1 (IRG1))
    别名
    ACOD1 (IRG1 产品)
    别名
    CAD antibody, AI323667 antibody, aconitate decarboxylase 1 antibody, ACOD1 antibody, Acod1 antibody
    背景
    Involved in the inhibition of the inflammatory response. Acts as a negative regulator of the Toll-like receptors (TLRs)-mediated inflammatory innate response by stimulating the tumor necrosis factor alpha-induced protein TNFAIP3 expression via reactive oxygen species (ROS) in LPS-tolerized macrophages. Involved in antimicrobial response of innate immune cells, ACOD1-mediated itaconic acid production contributes to the antimicrobial activity of macrophages. Plays a role in the embryo implantation.
    分子量

    Observed_MW: Refer to figures

    Calculated_MW: 53 kDa

    UniProt
    A6NK06
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