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- 抗原 See all IRG1 products
- IRG1 (Immunoresponsive Gene 1 (IRG1))
- 适用
- 人, 小鼠
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宿主
- 兔
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克隆类型
- 多克隆
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标记
- This IRG1 antibody is un-conjugated
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应用范围
- ELISA, Western Blotting (WB)
- 产品特性
- Polyclonal Antibody
- 纯化方法
- Antigen affinity purification
- 免疫原
- Synthetic peptide of human ACOD1
- 亚型
- IgG
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anti-Immunoresponsive Gene 1 (IRG1) (AA 57-257) antibody
IRG1 适用: 人 ELISA, IHC 宿主: 兔 Polyclonal unconjugated
anti-Immunoresponsive Gene 1 (IRG1) (C-Term) antibodyIRG1 适用: 人 ELISA, WB, ICC, IF 宿主: 兔 Polyclonal unconjugated
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- 应用备注
- WB 1:500-1:2000, ELISA 1:5000-1:10000
- 限制
- 仅限研究用
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- 状态
- Liquid
- 浓度
- 1.32 mg/mL
- 缓冲液
- PBS with 0.05 % Sodium azide and 40 % Glycerol, pH 7.4
- 储存液
- Sodium azide
- 注意事项
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
- 储存条件
- -20 °C
- 储存方法
- Store at -20°C. Avoid freeze / thaw cycles.
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- 抗原
- IRG1 (Immunoresponsive Gene 1 (IRG1))
- 别名
- ACOD1 (IRG1 产品)
- 别名
- CAD antibody, AI323667 antibody, aconitate decarboxylase 1 antibody, ACOD1 antibody, Acod1 antibody
- 背景
- Involved in the inhibition of the inflammatory response. Acts as a negative regulator of the Toll-like receptors (TLRs)-mediated inflammatory innate response by stimulating the tumor necrosis factor alpha-induced protein TNFAIP3 expression via reactive oxygen species (ROS) in LPS-tolerized macrophages. Involved in antimicrobial response of innate immune cells, ACOD1-mediated itaconic acid production contributes to the antimicrobial activity of macrophages. Plays a role in the embryo implantation.
- 分子量
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Observed_MW: Refer to figures
Calculated_MW: 53 kDa
- UniProt
- A6NK06
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