HIST1H2BA 抗体
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- 抗原 See all HIST1H2BA products
- HIST1H2BA (Histone Cluster 1, H2ba (HIST1H2BA))
- 适用
- 人, 小鼠, 大鼠
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宿主
- 兔
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克隆类型
- 多克隆
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标记
- This HIST1H2BA antibody is un-conjugated
- 应用范围
- Western Blotting (WB), ELISA, Immunohistochemistry (IHC)
- 产品特性
- Polyclonal Antibody
- 纯化方法
- Antigen affinity purification
- 免疫原
- Synthetic peptide of human HIST1H2BA
- 亚型
- IgG
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- 应用备注
- WB 1:500-1:2000, IHC 1:50-1:300, ELISA 1:5000-1:10000
- 限制
- 仅限研究用
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- 状态
- Liquid
- 浓度
- 1.98 mg/mL
- 缓冲液
- PBS with 0.05 % Sodium azide and 40 % Glycerol, pH 7.4
- 储存液
- Sodium azide
- 注意事项
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
- 储存条件
- -20 °C
- 储存方法
- Store at -20°C. Avoid freeze / thaw cycles.
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- 抗原
- HIST1H2BA (Histone Cluster 1, H2ba (HIST1H2BA))
- 别名
- HIST1H2BA (HIST1H2BA 产品)
- 别名
- H2BFU antibody, STBP antibody, TSH2B antibody, bA317E16.3 antibody, Th2b antibody, histone cluster 1 H2B family member a antibody, histone cluster 1, H2ba antibody, HIST1H2BA antibody, Hist1h2ba antibody
- 背景
- The nucleosome, made up of four core histone proteins (H2A, H2B, H3, and H4), is the primary building block of chromatin. Originally thought to function as a static scaffold for DNA packaging, histones have now been shown to be dynamic proteins, undergoing multiple types of post-translational modifications, including acetylation, phosphorylation, methylation, and ubiquitination , acetylation of specific lysine residues creates docking sites that facilitate recruitment of many transcription and chromatin regulatory proteins that contain a bromodomain, which binds to acetylated lysine residues . Histone H2B is rapidly phosphorylated at irradiation-induced DNA damage foci in mouse embryonic fibroblasts .
- 分子量
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Observed_MW: Refer to figures
Calculated_MW: 14 kDa
- UniProt
- Q96A08
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