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HIST1H2BA 抗体

This anti-HIST1H2BA antibody is a 兔 多克隆 antibody detecting HIST1H2BA in WB, ELISA 和 IHC. Suitable for 人, 小鼠 和 大鼠.
产品编号 ABIN7248536
发货至: 中国

Quick Overview for HIST1H2BA 抗体 (ABIN7248536)

抗原

HIST1H2BA (Histone Cluster 1, H2ba (HIST1H2BA))

适用

人, 小鼠, 大鼠

宿主

  • 21
  • 1

克隆类型

  • 21
  • 1
多克隆

标记

  • 10
  • 2
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
This HIST1H2BA antibody is un-conjugated

应用范围

Western Blotting (WB), ELISA, Immunohistochemistry (IHC)
  • 产品特性

    Polyclonal Antibody

    纯化方法

    Antigen affinity purification

    免疫原

    Synthetic peptide of human HIST1H2BA

    亚型

    IgG
  • 应用备注

    WB 1:500-1:2000, IHC 1:50-1:300, ELISA 1:5000-1:10000

    限制

    仅限研究用
  • 状态

    Liquid

    浓度

    1.98 mg/mL

    缓冲液

    PBS with 0.05 % Sodium azide and 40 % Glycerol, pH 7.4

    储存液

    Sodium azide

    注意事项

    This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

    储存条件

    -20 °C

    储存方法

    Store at -20°C. Avoid freeze / thaw cycles.
  • 抗原

    HIST1H2BA (Histone Cluster 1, H2ba (HIST1H2BA))

    别名

    HIST1H2BA

    背景

    The nucleosome, made up of four core histone proteins (H2A, H2B, H3, and H4), is the primary building block of chromatin. Originally thought to function as a static scaffold for DNA packaging, histones have now been shown to be dynamic proteins, undergoing multiple types of post-translational modifications, including acetylation, phosphorylation, methylation, and ubiquitination , acetylation of specific lysine residues creates docking sites that facilitate recruitment of many transcription and chromatin regulatory proteins that contain a bromodomain, which binds to acetylated lysine residues . Histone H2B is rapidly phosphorylated at irradiation-induced DNA damage foci in mouse embryonic fibroblasts .

    分子量

    Observed_MW: Refer to figures

    Calculated_MW: 14 kDa

    UniProt

    Q96A08
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