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CEND1 抗体

CEND1 适用: 人, 小鼠, 大鼠 ELISA, WB, IHC 宿主: 兔 Polyclonal unconjugated
产品编号 ABIN7248425
发货至: 中国
  • 抗原 See all CEND1 抗体
    CEND1 (Cell Cycle Exit and Neuronal Differentiation 1 (CEND1))
    适用
    • 14
    • 12
    • 12
    • 2
    • 1
    • 1
    • 1
    人, 小鼠, 大鼠
    宿主
    • 14
    • 1
    克隆类型
    • 13
    • 2
    多克隆
    标记
    • 8
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    This CEND1 antibody is un-conjugated
    应用范围
    • 6
    • 3
    • 3
    • 2
    • 2
    • 1
    • 1
    • 1
    ELISA, Western Blotting (WB), Immunohistochemistry (IHC)
    产品特性
    Polyclonal Antibody
    纯化方法
    Antigen affinity purification
    免疫原
    Synthetic peptide of human CEND1
    亚型
    IgG
  • 应用备注
    WB 1:500-1:2000, IHC 1:40-1:200, ELISA 1:5000-1:10000
    限制
    仅限研究用
  • 状态
    Liquid
    浓度
    0.9 mg/mL
    缓冲液
    PBS with 0.05 % Sodium azide and 40 % Glycerol, pH 7.4
    储存液
    Sodium azide
    注意事项
    This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
    储存条件
    -20 °C
    储存方法
    Store at -20°C. Avoid freeze / thaw cycles.
  • 抗原
    CEND1 (Cell Cycle Exit and Neuronal Differentiation 1 (CEND1))
    别名
    CEND1 (CEND1 产品)
    别名
    BM88 antibody, 1500001H12Rik antibody, AI415214 antibody, C38 antibody, RGD1309401 antibody, cell cycle exit and neuronal differentiation 1 antibody, CEND1 antibody, Cend1 antibody
    背景
    BM88, also known as CEND1 (cell cycle exit and neuronal differentiation protein 1), is a 149 amino acid protein that belongs to the CEND1 familly. Involved in neuroblastoma cell differentiation, BM88 is a single-pass type IV membrane protein that is neuron specific. It is suggested that BM88 forms a dimer of two identical polypeptides linked by disulfide bridges. BM88 has a central proline-rich region containing four PxxP motifs, which typically bind SRC homology-3 (SH3) domains, as well as a putative C-terminal transmembrane region, and several potential sites for N-glycosylation, myristoylation and phosphorylation. It is also suggested that a novel signaling mechanism exists by which BM88 interferes with calcium release from inositol 1,4,5-trisphosphate-sensitive stores and exerts anti-proliferative and anti-apoptotic functions. BM88 is an important molecular target for HDAC inhibition, and transcription of BM88 is induced by trichostatin-A.
    分子量

    Observed_MW: Refer to figures

    Calculated_MW: 15 kDa

    UniProt
    Q8N111
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