ABC42 antibody, ALD antibody, ALDP antibody, AMN antibody, RGD1562128 antibody, zgc:172102 antibody, ABCD1 antibody, Ald antibody, Aldgh antibody, ATP binding cassette subfamily D member 1 antibody, ATP-binding cassette, sub-family D (ALD), member 1 antibody, ATP-binding cassette sub-family D member 1 antibody, ATP binding cassette subfamily D member 1 L homeolog antibody, ABCD1 antibody, Abcd1 antibody, abcd1 antibody, CpipJ_CPIJ013253 antibody, VDBG_05717 antibody, abcd1.L antibody
背景
ABCD1 (also known as ALDP) is a member of the ATP-binding cassette (ABC) transporter superfamily which functions as transporter for a wide variety of substrates. It localizes to the peroxisomal membrane. The exact function is not clear so far. Various mutations of ABCD1 cause X-linked adrenoleukodystrophy (X-ALD),an inherited neurodegenerative disease affecting the nervous system white matter and adrenal cortex.