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HIPK3 抗体

HIPK3 适用: 人, 小鼠, 大鼠 ELISA, IHC 宿主: 兔 Polyclonal unconjugated
产品编号 ABIN7247966
发货至: 中国
  • 抗原 See all HIPK3 抗体
    HIPK3 (Homeodomain Interacting Protein Kinase 3 (HIPK3))
    适用
    人, 小鼠, 大鼠
    宿主
    • 49
    克隆类型
    • 49
    多克隆
    标记
    • 11
    • 6
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    • 3
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    This HIPK3 antibody is un-conjugated
    应用范围
    • 25
    • 19
    • 18
    • 13
    • 13
    • 7
    • 3
    • 2
    • 1
    • 1
    ELISA, Immunohistochemistry (IHC)
    产品特性
    Polyclonal Antibody
    纯化方法
    Antigen affinity purification
    免疫原
    Synthetic peptide of human HIPK3
    亚型
    IgG
    Top Product
    Discover our top product HIPK3 Primary Antibody
  • 应用备注
    IHC 1:50-1:300, ELISA 1:5000-1:10000
    限制
    仅限研究用
  • 状态
    Liquid
    浓度
    0.6 mg/mL
    缓冲液
    PBS with 0.05 % Sodium azide and 40 % Glycerol, pH 7.4
    储存液
    Sodium azide
    注意事项
    This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
    储存条件
    -20 °C
    储存方法
    Store at -20°C. Avoid freeze / thaw cycles.
  • 抗原
    HIPK3 (Homeodomain Interacting Protein Kinase 3 (HIPK3))
    别名
    HIPK3 (HIPK3 产品)
    别名
    HIPK3 antibody, pky antibody, yak1 antibody, dyrk6 antibody, fist3 antibody, MGC145460 antibody, DYRK6 antibody, FIST3 antibody, PKY antibody, YAK1 antibody, ANPK antibody, homeodomain interacting protein kinase 3 antibody, homeodomain interacting protein kinase 3 L homeolog antibody, HIPK3 antibody, hipk3.L antibody, hipk3 antibody, Hipk3 antibody
    背景
    Serine/threonine-protein kinase involved in transcription regulation, apoptosis and steroidogenic gene expression. Phosphorylates JUN and RUNX2. Seems to negatively regulate apoptosis by promoting FADD phosphorylation. Enhances androgen receptor-mediated transcription. May act as a transcriptional corepressor for NK homeodomain transcription factors. The phosphorylation of NR5A1 activates SF1 leading to increased steroidogenic gene expression upon cAMP signaling pathway stimulation. In osteoblasts, supports transcription activation: phosphorylates RUNX2 that synergizes with SPEN/MINT to enhance FGFR2-mediated activation of the osteocalcin FGF-responsive element (OCFRE).
    UniProt
    Q9H422
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