CKMT1 抗体
-
- 抗原 See all CKMT1 抗体
- CKMT1 (Creatine Kinase, Mitochondrial 1, Ubiquitous (CKMT1))
-
适用
- 人
-
宿主
- 兔
-
克隆类型
- 多克隆
-
标记
- This CKMT1 antibody is un-conjugated
-
应用范围
- Western Blotting (WB), ELISA, Immunohistochemistry (IHC)
- 产品特性
- Polyclonal Antibody
- 纯化方法
- Antigen affinity purification
- 免疫原
- Synthetic peptide of human CKMT1A/CKMT1B
- 亚型
- IgG
-
-
- 应用备注
- WB 1:500-1:2000, IHC 1:40-1:200, ELISA 1:5000-1:10000
- 限制
- 仅限研究用
-
- 状态
- Liquid
- 浓度
- 1.68 mg/mL
- 缓冲液
- PBS with 0.05 % Sodium azide and 40 % Glycerol, pH 7.4
- 储存液
- Sodium azide
- 注意事项
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
- 储存条件
- -20 °C
- 储存方法
- Store at -20°C. Avoid freeze / thaw cycles.
-
- 抗原
- CKMT1 (Creatine Kinase, Mitochondrial 1, Ubiquitous (CKMT1))
- 别名
- CKMT1A/CKMT1B (CKMT1 产品)
- 别名
- fb37h03 antibody, fb69a12 antibody, wu:fb37h03 antibody, wu:fb69a12 antibody, Mt-CK antibody, ScCKmit antibody, UbCKmit antibody, mi-CK antibody, Ckmt1 antibody, creatine kinase, mitochondrial 1 antibody, creatine kinase, mitochondrial 1, ubiquitous antibody, ckmt1 antibody, Ckmt1 antibody
- 背景
- Mitochondrial creatine (MtCK) kinase is responsible for the transfer of high energy phosphate from mitochondria to the cytosolic carrier, creatine. It belongs to the creatine kinase isoenzyme family. It exists as two isoenzymes, sarcomeric MtCK and ubiquitous MtCK, encoded by separate genes. Mitochondrial creatine kinase occurs in two different oligomeric forms: dimers and octamers, in contrast to the exclusively dimeric cytosolic creatine kinase isoenzymes. Many malignant cancers with poor prognosis have shown overexpression of ubiquitous mitochondrial creatine kinase, this may be related to high energy turnover and failure to eliminate cancer cells via apoptosis. Ubiquitous mitochondrial creatine kinase has 80 % homology with the coding exons of sarcomeric mitochondrial creatine kinase. Two genes located near each other on chromosome 15 have been identified which encode identical mitochondrial creatine kinase proteins.
- 分子量
-
Observed_MW: Refer to figures
Calculated_MW: 47 kDa
- UniProt
- P12532
-