Foxk1 抗体
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- 抗原 See all Foxk1 抗体
- Foxk1 (Forkhead Box K1 (Foxk1))
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适用
- 人, 小鼠
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宿主
- 兔
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克隆类型
- 多克隆
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标记
- This Foxk1 antibody is un-conjugated
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应用范围
- Western Blotting (WB), ELISA
- 产品特性
- Polyclonal Antibody
- 纯化方法
- Antigen affinity purification
- 免疫原
- Synthetic peptide of human FOXK1
- 亚型
- IgG
- Top Product
- Discover our top product Foxk1 Primary Antibody
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- 应用备注
- WB 1:500-1:2000, ELISA 1:5000-1:10000
- 限制
- 仅限研究用
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- 状态
- Liquid
- 浓度
- 1.5 mg/mL
- 缓冲液
- PBS with 0.05 % Sodium azide and 40 % Glycerol, pH 7.4
- 储存液
- Sodium azide
- 注意事项
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
- 储存条件
- -20 °C
- 储存方法
- Store at -20°C. Avoid freeze / thaw cycles.
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- 抗原
- Foxk1 (Forkhead Box K1 (Foxk1))
- 别名
- FOXK1 (Foxk1 产品)
- 别名
- FOXK1L antibody, A630048H08Rik antibody, AI463295 antibody, ENSMUSG00000075577 antibody, Gm10868 antibody, Mnf antibody, RGD1309643 antibody, wu:fi75f05 antibody, zgc:66237 antibody, FOXK1 antibody, forkhead box K1 antibody, FOXK1 antibody, Foxk1 antibody, foxk1 antibody
- 背景
- The FOX family of transcription factors share a common DIUA binding domain termed a winged-helix or forkhead domain. Many FOX proteins play important roles in development, metabolism, cancer and aging. In skeletal muscles, undifferentiated myogenic stem cells (satellite cells) can mobilize to regenerate myofibers in response to injury. FOXK1 is expressed in these cells and regulates cell cycle progression through an interaction with its downstream target the cyclin-dependent kinase inhibitor p21 (CIP). Loss of FOXK1 in mice results in growth retardation and a severe impairment in skeletal muscle regeneration following injury. FOXK1 also shows expression in immature tissues of brain, eye, heart, lung and thymus. It also is predominantly expressed in many malignant tissues, such as tumors of the brain, colon and lymph node.
- 分子量
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Observed_MW: Refer to figures
Calculated_MW: 75 kDa
- UniProt
- P85037
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