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ELF3 抗体

ELF3 适用: 人 ELISA, IHC 宿主: 兔 Polyclonal unconjugated
产品编号 ABIN7247069
发货至: 中国
  • 抗原 See all ELF3 抗体
    ELF3 (E74-Like Factor 3 (Ets Domain Transcription Factor, Epithelial-Specific) (ELF3))
    适用
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    宿主
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    克隆类型
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    多克隆
    标记
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    This ELF3 antibody is un-conjugated
    应用范围
    • 56
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    ELISA, Immunohistochemistry (IHC)
    产品特性
    Polyclonal Antibody
    纯化方法
    Antigen affinity purification
    免疫原
    Fusion protein of human ELF3
    亚型
    IgG
    Top Product
    Discover our top product ELF3 Primary Antibody
  • 应用备注
    IHC 1:50-1:300, ELISA 1:5000-1:10000
    限制
    仅限研究用
  • 状态
    Liquid
    浓度
    1.68 mg/mL
    缓冲液
    PBS with 0.05 % Sodium azide and 40 % Glycerol, pH 7.4
    储存液
    Sodium azide
    注意事项
    This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
    储存条件
    -20 °C
    储存方法
    Store at -20°C. Avoid freeze / thaw cycles.
  • 抗原
    ELF3 (E74-Like Factor 3 (Ets Domain Transcription Factor, Epithelial-Specific) (ELF3))
    别名
    ELF3 (ELF3 产品)
    别名
    ert antibody, esx antibody, epr-1 antibody, ese-1 antibody, ESE-1 antibody, ESX antibody, jen antibody, EPR-1 antibody, ERT antibody, E74 like ETS transcription factor 3 antibody, E74-like factor 3 antibody, elf3 antibody, Elf3 antibody, ELF3 antibody
    背景
    Transcriptional activator that binds and transactivates ETS sequences containing the consensus nucleotide core sequence GGA[AT]. Acts synergistically with POU2F3 to transactivate the SPRR2A promoter and with RUNX1 to transactivate the ANGPT1 promoter. Also transactivates collagenase, CCL20, CLND7, FLG, KRT8, NOS2, PTGS2, SPRR2B, TGFBR2 and TGM3 promoters. Represses KRT4 promoter activity. Involved in mediating vascular inflammation. May play an important role in epithelial cell differentiation and tumorigenesis. May be a critical downstream effector of the ERBB2 signaling pathway. May be associated with mammary gland development and involution. Plays an important role in the regulation of transcription with TATA-less promoters in preimplantation embryos, which is essential in preimplantation development (By similarity).
    UniProt
    P78545
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