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PNRC2 抗体

PNRC2 适用: 人, 大鼠, 小鼠 ELISA, IHC 宿主: 兔 Polyclonal unconjugated
产品编号 ABIN7246772
发货至: 中国
  • 抗原 See all PNRC2 抗体
    PNRC2 (Proline Rich Nuclear Receptor Coactivator 2 (PNRC2))
    适用
    • 20
    • 11
    • 10
    • 4
    • 3
    • 3
    • 2
    • 2
    • 2
    • 2
    • 1
    • 1
    人, 大鼠, 小鼠
    宿主
    • 20
    克隆类型
    • 20
    多克隆
    标记
    • 9
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    This PNRC2 antibody is un-conjugated
    应用范围
    • 9
    • 6
    • 3
    • 1
    • 1
    ELISA, Immunohistochemistry (IHC)
    产品特性
    Polyclonal Antibody
    纯化方法
    Antigen affinity purification
    免疫原
    Fusion protein of human PNRC2
    亚型
    IgG
    Top Product
    Discover our top product PNRC2 Primary Antibody
  • 应用备注
    IHC 1:30-1:150, ELISA 1:5000-1:10000
    限制
    仅限研究用
  • 状态
    Liquid
    浓度
    0.54 mg/mL
    缓冲液
    PBS with 0.05 % Sodium azide and 40 % Glycerol, pH 7.4
    储存液
    Sodium azide
    注意事项
    This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
    储存条件
    -20 °C
    储存方法
    Store at -20°C. Avoid freeze / thaw cycles.
  • 抗原
    PNRC2 (Proline Rich Nuclear Receptor Coactivator 2 (PNRC2))
    别名
    PNRC2 (PNRC2 产品)
    别名
    0610011E17Rik antibody, D4Bwg0593e antibody, wu:cegs2777 antibody, wu:fb51a04 antibody, wu:fb81a06 antibody, wu:fd19g06 antibody, proline rich nuclear receptor coactivator 2 antibody, proline-rich nuclear receptor coactivator 2 antibody, PNRC2 antibody, Pnrc2 antibody, pnrc2 antibody
    背景
    Involved in nonsense-mediated mRNA decay (NMD) by acting as a bridge between the mRNA decapping complex and the NMD machinery (PubMed:19150429). May act by targeting the NMD machinery to the P-body and recruiting the decapping machinery to aberrant mRNAs (PubMed:19150429). Required for UPF1/RENT1 localization to the P-body (PubMed:19150429). Plays a role in glucocorticoid receptor-mediated mRNA degradation by interacting with the glucocorticoid receptor NR3C1 in a ligand-dependent manner when it is bound to the 5' UTR of target mRNAs and recruiting the RNA helicase UPF1 and the mRNA-decapping enzyme DCP1A, leading to RNA decay (PubMed:25775514). Also acts as a nuclear receptor coactivator (PubMed:11574675). May play a role in controlling the energy balance between energy storage and energy expenditure (By similarity).
    UniProt
    Q9NPJ4
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