PSMD12 抗体
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- 抗原 See all PSMD12 抗体
- PSMD12 (Proteasome (Prosome, Macropain) 26S Subunit, Non-ATPase, 12 (PSMD12))
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适用
- 人, 小鼠, 大鼠
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宿主
- 兔
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克隆类型
- 多克隆
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标记
- This PSMD12 antibody is un-conjugated
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应用范围
- Western Blotting (WB), ELISA, Immunohistochemistry (IHC)
- 产品特性
- Polyclonal Antibody
- 纯化方法
- Antigen affinity purification
- 免疫原
- Fusion protein of human PSMD12
- 亚型
- IgG
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- 应用备注
- WB 1:500-1:2000, IHC 1:40-1:200, ELISA 1:5000-1:10000
- 限制
- 仅限研究用
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- 状态
- Liquid
- 浓度
- 0.72 mg/mL
- 缓冲液
- PBS with 0.05 % Sodium azide and 40 % Glycerol, pH 7.4
- 储存液
- Sodium azide
- 注意事项
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
- 储存条件
- -20 °C
- 储存方法
- Store at -20°C. Avoid freeze / thaw cycles.
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- 抗原
- PSMD12 (Proteasome (Prosome, Macropain) 26S Subunit, Non-ATPase, 12 (PSMD12))
- 别名
- PSMD12 (PSMD12 产品)
- 背景
- The 26S proteasome is a multicatalytic proteinase complex with a highly ordered structure composed of 2 complexes, a 20S core and a 19S regulator. The 20S core is composed of 4 rings of 28 non-identical subunits, 2 rings are composed of 7 alpha subunits and 2 rings are composed of 7 beta subunits. The 19S regulator is composed of a base, which contains 6 ATPase subunits and 2 non-ATPase subunits, and a lid, which contains up to 10 non-ATPase subunits. Proteasomes are distributed throughout eukaryotic cells at a high concentration and cleave peptides in an ATP/ubiquitin-dependent process in a non-lysosomal pathway. An essential function of a modified proteasome, the immunoproteasome, is the processing of class I MHC peptides. This gene encodes a non-ATPase subunit of the 19S regulator. A pseudogene has been identified on chromosome 3. Alternatively spliced transcript variants encoding different isoforms have been found for this gene.
- 分子量
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Observed_MW: Refer to figures
Calculated_MW: 53 kDa
- UniProt
- O00232
- 途径
- Mitotic G1-G1/S Phases, DNA Replication, Synthesis of DNA, Ubiquitin Proteasome Pathway
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