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RNF111 抗体

RNF111 适用: 人 ELISA, IHC 宿主: 兔 Polyclonal unconjugated
产品编号 ABIN7246457
发货至: 中国
  • 抗原 See all RNF111 抗体
    RNF111 (Ring Finger Protein 111 (RNF111))
    适用
    • 38
    • 32
    • 22
    宿主
    • 49
    • 4
    克隆类型
    • 51
    • 2
    多克隆
    标记
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    This RNF111 antibody is un-conjugated
    应用范围
    • 25
    • 22
    • 13
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    • 4
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    ELISA, Immunohistochemistry (IHC)
    产品特性
    Polyclonal Antibody
    纯化方法
    Antigen affinity purification
    免疫原
    Fusion protein of human RNF111
    亚型
    IgG
    Top Product
    Discover our top product RNF111 Primary Antibody
  • 应用备注
    IHC 1:50-1:300, ELISA 1:5000-1:10000
    限制
    仅限研究用
  • 状态
    Liquid
    浓度
    0.84 mg/mL
    缓冲液
    PBS with 0.05 % Sodium azide and 40 % Glycerol, pH 7.4
    储存液
    Sodium azide
    注意事项
    This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
    储存条件
    -20 °C
    储存方法
    Store at -20°C. Avoid freeze / thaw cycles.
  • 抗原
    RNF111 (Ring Finger Protein 111 (RNF111))
    别名
    RNF111 (RNF111 产品)
    别名
    ARK antibody, Arkadia antibody, RNF111 antibody, rnf111 antibody, ark antibody, MGC81253 antibody, MGC146379 antibody, ring finger protein 111 antibody, ring finger 111 antibody, RNF111 antibody, Rnf111 antibody, rnf111-b antibody, rnf111 antibody
    背景
    The protein encoded by this gene is a nuclear RING-domain containing E3 ubiquitin ligase. This protein interacts with the transforming growth factor (TGF) -beta/NODAL signaling pathway by promoting the ubiquitination and proteosomal degradation of negative regulators, like SMAD proteins, and thereby enhances TGF-beta target-gene transcription. As a modulator of the nodal signaling cascade, this gene plays a critical role in the induction of mesoderm during embryonic development. Alternative splicing of this gene results in multiple transcript variants encoding distinct isoforms.
    UniProt
    Q6ZNA4
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