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LSM10 抗体

LSM10 适用: 人, 小鼠 ELISA, IHC 宿主: 兔 Polyclonal unconjugated
产品编号 ABIN7246445
发货至: 中国
  • 抗原 See all LSM10 抗体
    LSM10 (LSM10, U7 Small Nuclear RNA Associated (LSM10))
    适用
    • 17
    • 9
    • 2
    • 1
    • 1
    • 1
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    • 1
    • 1
    人, 小鼠
    宿主
    • 14
    • 3
    克隆类型
    • 14
    • 3
    多克隆
    标记
    • 7
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
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    This LSM10 antibody is un-conjugated
    应用范围
    • 5
    • 5
    • 2
    • 2
    • 1
    • 1
    ELISA, Immunohistochemistry (IHC)
    产品特性
    Polyclonal Antibody
    纯化方法
    Antigen affinity purification
    免疫原
    Fusion protein of human LSM10
    亚型
    IgG
    Top Product
    Discover our top product LSM10 Primary Antibody
  • 应用备注
    IHC 1:50-1:300, ELISA 1:5000-1:10000
    限制
    仅限研究用
  • 状态
    Liquid
    浓度
    0.9 mg/mL
    缓冲液
    PBS with 0.05 % Sodium azide and 40 % Glycerol, pH 7.4
    储存液
    Sodium azide
    注意事项
    This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
    储存条件
    -20 °C
    储存方法
    Store at -20°C. Avoid freeze / thaw cycles.
  • 抗原
    LSM10 (LSM10, U7 Small Nuclear RNA Associated (LSM10))
    别名
    LSM10 (LSM10 产品)
    别名
    MST074 antibody, MSTP074 antibody, LSM10, U7 small nuclear RNA associated antibody, U7 snRNP-specific Sm-like protein LSM10 antibody, LSM10 antibody, lsm10 antibody, Lsm10 antibody
    背景
    LSm10 (U7 snRNA-associated Sm-like protein LSm10) is a nuclear protein that belongs to the snRNP (small nuclear ribonucleoproteins) Sm protein family. The survival of motor neurons (SMN) complex mediates the assembly of snRNPs involved in splicing and histone RNA processing. A crucial step in this process is the binding of Sm proteins onto the SMN protein. LSm10 and LSm11, mammalian homologs of the yeast Sm proteins D1 and D2, are important for U7 snRNP function and subcellular localization. U7 snRNP is an RNA molecule involved in the splicing of animal histone pre-mRNAs. Lsm10 and Lsm11 also associate with pICln (Chloride ion current inducer protein), which interacts with Sm proteins to inhibit their assembly on U RNA. LSm10 interactions with U7 snRNA and pICln may provide the means for using modified U7 snRNA derivatives to alter specific pre-mRNA splicing events, potentially leading to advances in antisense gene therapy.
    UniProt
    Q969L4
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