TUBGCP4 抗体
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- 抗原 See all TUBGCP4 抗体
- TUBGCP4 (Tubulin, gamma Complex Associated Protein 4 (TUBGCP4))
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适用
- 人, 小鼠
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宿主
- 兔
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克隆类型
- 多克隆
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标记
- This TUBGCP4 antibody is un-conjugated
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应用范围
- ELISA, Western Blotting (WB)
- 产品特性
- Polyclonal Antibody
- 纯化方法
- Antigen affinity purification
- 免疫原
- Fusion protein of human TUBGCP4
- 亚型
- IgG
- Top Product
- Discover our top product TUBGCP4 Primary Antibody
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- 应用备注
- WB 1:500-1:2000, ELISA 1:5000-1:10000
- 限制
- 仅限研究用
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- 状态
- Liquid
- 浓度
- 0.6 mg/mL
- 缓冲液
- PBS with 0.05 % Sodium azide and 40 % Glycerol, pH 7.4
- 储存液
- Sodium azide
- 注意事项
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
- 储存条件
- -20 °C
- 储存方法
- Store at -20°C. Avoid freeze / thaw cycles.
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- 抗原
- TUBGCP4 (Tubulin, gamma Complex Associated Protein 4 (TUBGCP4))
- 别名
- TUBGCP4 (TUBGCP4 产品)
- 别名
- RGD1306924 antibody, 76p antibody, MGC81229 antibody, zgc:194561 antibody, zgc:194580 antibody, DKFZp459O2210 antibody, 76P antibody, GCP-4 antibody, GCP4 antibody, h76p antibody, hGCP4 antibody, hGrip76 antibody, 4932441P04Rik antibody, D2Ertd435e antibody, tubulin, gamma complex associated protein 4 antibody, tubulin gamma complex associated protein 4 antibody, tubulin gamma complex associated protein 4 L homeolog antibody, Tubgcp4 antibody, TUBGCP4 antibody, tubgcp4.L antibody, tubgcp4 antibody
- 背景
- This gene encodes a component of the gamma-tubulin ring complex, which is required for microtubule nucleation. In mammalian cells, the protein localizes to centrosomes in association with gamma-tubulin. Crystal structure analysis revealed a structure composed of five helical bundles arranged around conserved hydrophobic cores. An exposed surface area located in the C-terminal domain is essential and sufficient for direct binding to gamma-tubulin. Mutations in this gene that alter microtubule organization are associated with microcephaly and chorioretinopathy. Alternative splicing results in multiple transcript variants.TUBGCP4 (Tubulin Gamma Complex Associated Protein 4) is a Protein Coding gene. Diseases associated with TUBGCP4 include Microcephaly And Chorioretinopathy, Autosomal Recessive, 3 and Autosomal Recessive Chorioretinopathy-Microcephaly Syndrome. Among its related pathways are Regulation of PLK1 Activity at G2/M Transition and Cell Cycle, Mitotic. GO annotations related to this gene include structural constituent of cytoskeleton. An important paralog of this gene is TUBGCP6.
- 分子量
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Observed_MW: Refer to figures
Calculated_MW: 76 kDa
- UniProt
- Q9UGJ1
- 途径
- M Phase
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