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IGHA1 抗体

IGHA1 适用: 人 IHC, ELISA 宿主: 兔 Polyclonal unconjugated
产品编号 ABIN7246370
发货至: 中国
  • 抗原 See all IGHA1 products
    IGHA1 (Immunoglobulin Heavy Constant alpha 1 (IGHA1))
    适用
    • 16
    • 2
    • 2
    宿主
    • 13
    • 3
    克隆类型
    • 13
    • 3
    多克隆
    标记
    • 9
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    This IGHA1 antibody is un-conjugated
    应用范围
    • 8
    • 7
    • 6
    • 4
    • 1
    • 1
    • 1
    • 1
    • 1
    Immunohistochemistry (IHC), ELISA
    产品特性
    Polyclonal Antibody
    纯化方法
    Antigen affinity purification
    免疫原
    Fusion protein of human IGHA1
    亚型
    IgG
  • 应用备注
    IHC 1:50-1:300, ELISA 1:5000-1:10000
    限制
    仅限研究用
  • 状态
    Liquid
    浓度
    1.14 mg/mL
    缓冲液
    PBS with 0.05 % Sodium azide and 40 % Glycerol, pH 7.4
    储存液
    Sodium azide
    注意事项
    This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
    储存条件
    -20 °C
    储存方法
    Store at -20°C. Avoid freeze / thaw cycles.
  • 抗原
    IGHA1 (Immunoglobulin Heavy Constant alpha 1 (IGHA1))
    别名
    IGHA1 (IGHA1 产品)
    别名
    IgA1 antibody, immunoglobulin heavy constant alpha 1 antibody, IGHA1 antibody
    背景
    Constant region of immunoglobulin heavy chains. Immunoglobulins, also known as antibodies, are membrane-bound or secreted glycoproteins produced by B lymphocytes. In the recognition phase of humoral immunity, the membrane-bound immunoglobulins serve as receptors which, upon binding of a specific antigen, trigger the clonal expansion and differentiation of B lymphocytes into immunoglobulins-secreting plasma cells. Secreted immunoglobulins mediate the effector phase of humoral immunity, which results in the elimination of bound antigens (PubMed:22158414, PubMed:20176268). The antigen binding site is formed by the variable domain of one heavy chain, together with that of its associated light chain. Thus, each immunoglobulin has two antigen binding sites with remarkable affinity for a particular antigen. The variable domains are assembled by a process called V-(D)-J rearrangement and can then be subjected to somatic hypermutations which, after exposure to antigen and selection, allow affinity maturation for a particular antigen (PubMed:17576170, PubMed:20176268). Ig alpha is the major immunoglobulin class in body secretions (PubMed:2241915).
    UniProt
    P01876
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