ATF6B 抗体
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- 抗原 See all ATF6B 抗体
- ATF6B (Activating Transcription Factor 6 beta (ATF6B))
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适用
- 人, 小鼠
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宿主
- 兔
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克隆类型
- 多克隆
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标记
- This ATF6B antibody is un-conjugated
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应用范围
- Western Blotting (WB), ELISA, Immunohistochemistry (IHC)
- 产品特性
- Polyclonal Antibody
- 纯化方法
- Antigen affinity purification
- 免疫原
- Fusion protein of human ATF6B
- 亚型
- IgG
- Top Product
- Discover our top product ATF6B Primary Antibody
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- 应用备注
- WB 1:500-1:2000, IHC 1:25-1:100, ELISA 1:5000-1:10000
- 限制
- 仅限研究用
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- 状态
- Liquid
- 浓度
- 0.5 mg/mL
- 缓冲液
- PBS with 0.05 % Sodium azide and 40 % Glycerol, pH 7.4
- 储存液
- Sodium azide
- 注意事项
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
- 储存条件
- -20 °C
- 储存方法
- Store at -20°C. Avoid freeze / thaw cycles.
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- 抗原
- ATF6B (Activating Transcription Factor 6 beta (ATF6B))
- 别名
- ATF6B (ATF6B 产品)
- 别名
- CREBL1 antibody, CREB-RP antibody, G13 antibody, AA617266 antibody, ATF6beta antibody, Creb-rp antibody, Crebl1 antibody, activating transcription factor 6 beta antibody, cyclic AMP-dependent transcription factor ATF-6 beta antibody, ATF6B antibody, LOC745411 antibody, Atf6b antibody
- 背景
- The protein encoded by this gene is a transcription factor in the unfolded protein response (UPR) pathway during ER stress. Either as a homodimer or as a heterodimer with ATF6-alpha, the encoded protein binds to the ER stress response element, interacting with nuclear transcription factor Y to activate UPR target genes. The protein is normally found in the membrane of the endoplasmic reticulum, however, under ER stress, the N-terminal cytoplasmic domain is cleaved from the rest of the protein and translocates to the nucleus. Two transcript variants encoding different isoforms have been found for this gene.
- 分子量
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Observed_MW: Refer to figures
Calculated_MW: 77 kDa
- UniProt
- Q99941
- 途径
- Thyroid Hormone Synthesis, Myometrial Relaxation and Contraction
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