KCNK10 antibody, K2p10.1 antibody, TREK-2 antibody, TREK2 antibody, 1700024D23Rik antibody, 3010005K24Rik antibody, Trek2 antibody, k2p10.1 antibody, trek-2 antibody, trek2 antibody, potassium two pore domain channel subfamily K member 10 antibody, potassium channel, subfamily K, member 10 antibody, potassium channel, two pore domain subfamily K, member 10 L homeolog antibody, KCNK10 antibody, Kcnk10 antibody, kcnk10.L antibody
背景
The protein encoded by this gene belongs to the family of potassium channel proteins containing two pore-forming P domains. This channel is an open rectifier which primarily passes outward current under physiological K+ concentrations, and is stimulated strongly by arachidonic acid and to a lesser degree by membrane stretching, intracellular acidification, and general anaesthetics. Several alternatively spliced transcript variants encoding different isoforms have been identified for this gene. KCNK10 (Potassium Two Pore Domain Channel Subfamily K Member 10) is a Protein Coding gene. Diseases associated with KCNK10 include Dentin Sensitivity. Among its related pathways are Cardiac conduction and Neuropathic Pain-Signaling in Dorsal Horn Neurons. GO annotations related to this gene include potassium channel activity and potassium ion leak channel activity. An important paralog of this gene is KCNK2.