KCHIP1 antibody, VABP antibody, kchip1 antibody, vabp antibody, KCNIP1 antibody, 2900046L02Rik antibody, 3202002F18Rik antibody, AI842357 antibody, AW494471 antibody, Kchip1.2 antibody, Kchip1 antibody, zgc:101531 antibody, potassium voltage-gated channel interacting protein 1 antibody, Kv channel interacting protein 1 L homeolog antibody, Kv channel-interacting protein 1 antibody, Kv channel interacting protein 1 b antibody, KCNIP1 antibody, kcnip1.L antibody, Kcnip1 antibody, kcnip1b antibody
背景
Human K(v) channel interacting protein 1 (KCHIP1) is a new member of the neural calcium binding protein superfamily. Members of the KCNIP family are small calcium binding proteins. They all have EF-hand-like domains,and differ from each other in the N-terminus. They are integral subunit components of native Kv4 channel complexes. They may regulate A-type currents,and hence neuronal excitability,in response to changes in intracellular calcium. KChIP1 is a neuronal calcium sensor protein that is predominantly expressed at GABAergic synapses and it has been related with modulation of K(+) channels,GABAergic transmission and cell death.