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- 抗原 See all C6orf150 抗体
- C6orf150 (Chromosome 6 Open Reading Frame 150 (C6orf150))
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适用
- 人
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宿主
- 兔
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克隆类型
- 多克隆
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标记
- This C6orf150 antibody is un-conjugated
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应用范围
- Western Blotting (WB), ELISA
- 产品特性
- Polyclonal Antibody
- 纯化方法
- Antigen affinity purification
- 免疫原
- Synthetic peptide of human MB21D1
- 亚型
- IgG
- Top Product
- Discover our top product C6orf150 Primary Antibody
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anti-Chromosome 6 Open Reading Frame 150 (C6orf150) (AA 211-395) antibody
C6orf150 适用: 小鼠 WB, IHC, IP, ICC 宿主: 兔 Polyclonal unconjugated
anti-Chromosome 6 Open Reading Frame 150 (C6orf150) (AA 350-522) antibodyC6orf150 适用: 人 WB, IHC, IP, IF 宿主: 兔 Polyclonal unconjugated
anti-Chromosome 6 Open Reading Frame 150 (C6orf150) (AA 1-185) antibodyC6orf150 适用: 人 WB 宿主: 小鼠 Monoclonal 7E3 unconjugated
anti-Chromosome 6 Open Reading Frame 150 (C6orf150) (pSer291) antibodyC6orf150 适用: 小鼠 WB 宿主: 兔 Polyclonal unconjugated
anti-Chromosome 6 Open Reading Frame 150 (C6orf150) (pSer420) antibodyC6orf150 适用: 小鼠 WB 宿主: 兔 Polyclonal unconjugated
anti-Chromosome 6 Open Reading Frame 150 (C6orf150) (AA 225-407) antibodyC6orf150 适用: 人 WB, IHC, ICC 宿主: 兔 Polyclonal unconjugated
anti-Chromosome 6 Open Reading Frame 150 (C6orf150) (Middle Region) antibodyC6orf150 适用: 人, Cow, 豚鼠, 马, Pig, 兔 WB 宿主: 兔 Polyclonal unconjugated
anti-Chromosome 6 Open Reading Frame 150 (C6orf150) (AA 273-303), (Middle Region) antibodyC6orf150 适用: 人 WB, EIA 宿主: 兔 Polyclonal unconjugated
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- 应用备注
- WB 1:500-1:2000, ELISA 1:5000-1:10000
- 限制
- 仅限研究用
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- 状态
- Liquid
- 浓度
- 0.78 mg/mL
- 缓冲液
- PBS with 0.05 % Sodium azide and 40 % Glycerol, pH 7.4
- 储存液
- Sodium azide
- 注意事项
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
- 储存条件
- -20 °C
- 储存方法
- Store at -20°C. Avoid freeze / thaw cycles.
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- 抗原
- C6orf150 (Chromosome 6 Open Reading Frame 150 (C6orf150))
- 别名
- CGAS (C6orf150 产品)
- 别名
- C6orf150 antibody, cGAS antibody, h-cGAS antibody, Mab-21 domain containing 1 antibody, cyclic GMP-AMP synthase antibody, MB21D1 antibody, CGAS antibody
- 背景
- Nucleotidyltransferase that catalyzes the formation of cyclic GMP-AMP (cGAMP) from ATP and GTP. Catalysis involves both the formation of a 2',5' phosphodiester linkage at the GpA step and the formation of a 3',5' phosphodiester linkage at the ApG step, producing c[G(2',5')pA(3',5')p]. Has antiviral activity by acting as a key cytosolic DNA sensor, the presence of double-stranded DNA (dsDNA) in the cytoplasm being a danger signal that triggers the immune responses. Binds cytosolic DNA directly, leading to activation and synthesis of cGAMP, a second messenger that binds to and activates TMEM173/STING, thereby triggering type-I interferon production. cGAMP can be transferred between cells by virtue of packaging within viral particles contributing to IFN-induction in newly infected cells in a cGAS-independent but TMEM173/STING-dependent manner (PubMed:26229115).
- 分子量
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Observed_MW: Refer to figures
Calculated_MW: 59 kDa
- UniProt
- Q8N884
- 途径
- Activation of Innate immune Response
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