CARD16 抗体
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- 抗原 See all CARD16 抗体
- CARD16 (Caspase Recruitment Domain Family, Member 16 (CARD16))
- 适用
- 人
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宿主
- 兔
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克隆类型
- 多克隆
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标记
- This CARD16 antibody is un-conjugated
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应用范围
- ELISA, Western Blotting (WB), Immunohistochemistry (IHC)
- 产品特性
- Polyclonal Antibody
- 纯化方法
- Antigen affinity purification
- 免疫原
- Synthetic peptide of human CARD16
- 亚型
- IgG
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- 应用备注
- WB 1:500-1:2000, IHC 1:40-1:200, ELISA 1:5000-1:10000
- 限制
- 仅限研究用
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- 状态
- Liquid
- 浓度
- 1.1 mg/mL
- 缓冲液
- PBS with 0.05 % Sodium azide and 40 % Glycerol, pH 7.4
- 储存液
- Sodium azide
- 注意事项
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
- 储存条件
- -20 °C
- 储存方法
- Store at -20°C. Avoid freeze / thaw cycles.
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- 抗原
- CARD16 (Caspase Recruitment Domain Family, Member 16 (CARD16))
- 别名
- CARD16 (CARD16 产品)
- 别名
- COP antibody, COP1 antibody, PSEUDO-ICE antibody, caspase recruitment domain family member 16 antibody, CARD16 antibody
- 背景
- Caspase inhibitor. Acts as a regulator of procaspase-1/CASP1 activation implicated in the regulation of the proteolytic maturation of pro-interleukin-1 beta (IL1B) and its release during inflammation. Inhibits the release of IL1B in response to LPS in monocytes. Also induces NF-kappa-B activation during the pro-inflammatory cytokine response. Also able to inhibit CASP1-mediated neuronal cell death, TNF-alpha, hypoxia-, UV-, and staurosporine-mediated cell death but not ER stress-mediated cell death. Acts by preventing activation of caspases CASP1 and CASP4, possibly by preventing the interaction between CASP1 and RIPK2.
- 分子量
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Observed_MW: Refer to figures
Calculated_MW: 23 kDa
- UniProt
- Q5EG05
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