HMG-R antibody, HMGA1A antibody, HMGIY antibody, Hmgi antibody, Hmgiy antibody, hmga1 antibody, hmgiy antibody, wu:fb12b06 antibody, wu:fb18f11 antibody, wu:fc19f01 antibody, wu:fi38b05 antibody, zgc:85677 antibody, AL023995 antibody, Hmga1a antibody, Hmga1b antibody, Hmgy antibody, HMG-I(Y) antibody, HMG-Y antibody, HMGA1 antibody, zgc:153948 antibody, high mobility group AT-hook 1 antibody, high mobility group protein HMG-I/HMG-Y antibody, high mobility group AT-hook 1a antibody, high mobility group AT-hook 1b antibody, HMGA1 antibody, Hmga1 antibody, TSC_c24220 antibody, hmga1a antibody, LOC705105 antibody, hmga1b antibody
背景
This gene encodes a non-histone protein involved in many cellular processes, including regulation of inducible gene transcription, integration of retroviruses into chromosomes, and the metastatic progression of cancer cells. The encoded protein preferentially binds to the minor groove of A+T-rich regions in double-stranded DNA. It has little secondary structure in solution but assumes distinct conformations when bound to substrates such as DNA or other proteins.