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EMP2 抗体

EMP2 适用: 人 IHC, ELISA 宿主: 兔 Polyclonal unconjugated
产品编号 ABIN7243274
发货至: 中国
  • 抗原 See all EMP2 products
    EMP2 (Epithelial Membrane Protein 2 (EMP2))
    适用
    • 17
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    宿主
    • 44
    克隆类型
    • 44
    多克隆
    标记
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    This EMP2 antibody is un-conjugated
    应用范围
    • 34
    • 18
    • 17
    • 13
    • 13
    • 8
    • 3
    • 1
    Immunohistochemistry (IHC), ELISA
    产品特性
    Polyclonal Antibody
    纯化方法
    Affinity purification
    免疫原
    Synthetic peptide of human EMP2
    亚型
    IgG
  • 应用备注
    IHC 1:50-1:200
    限制
    仅限研究用
  • 状态
    Liquid
    浓度
    0.8 mg/mL
    缓冲液
    PBS with 0.05 % sodium azide and 50 % glycerol, PH7.4
    储存液
    Sodium azide
    注意事项
    This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
    储存条件
    -20 °C
    储存方法
    Store at -20°C. Avoid freeze / thaw cycles.
  • 抗原
    EMP2 (Epithelial Membrane Protein 2 (EMP2))
    别名
    EMP2 (EMP2 产品)
    别名
    MGC52916 antibody, MGC130799 antibody, MGC69514 antibody, emp2 antibody, XMP antibody, epithelial membrane protein 2 L homeolog antibody, epithelial membrane protein 2 antibody, emp2.L antibody, emp2 antibody, EMP2 antibody, Emp2 antibody
    背景
    EMP-2 (epithelial membrane protein 2), also known as XMP, is a 167 amino acid multi-pass membrane protein that contains four-transmembrane domains and belongs to the GAS3/PMP22 (growth arrest-specific-3/peripheral myelin protein-22) family. Localized to lipid raft domains in the plasma membrane, EMP-2 regulates the expression of several target proteins and is necessary for blastocyst implantation in the uterine endometrium. Specifically, EMP-2 mediates blastocyst implantation by controlling the cell membrane expression of MHC and glycosylphosphatidylinositol-anchored proteins, as well as Integrins and caveolin-1. In adult tissues, EMP-2 is expressed in heart, lung, ovary and intestine, while fetal expression is highest in kidney, brain and liver. Overexpression of EMP-2 is associated with endometrial adenocarcinoma, suggesting a possible role for EMP-2 in tumorigenesis.
    NCBI登录号
    NP_001415
    UniProt
    P54851
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