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SPAG1 抗体

SPAG1 适用: 人 WB, ELISA 宿主: 兔 Polyclonal unconjugated
产品编号 ABIN7242443
发货至: 中国
  • 抗原 See all SPAG1 抗体
    SPAG1 (Sperm Associated Antigen 1 (SPAG1))
    适用
    • 29
    • 1
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    宿主
    • 28
    • 1
    克隆类型
    • 29
    多克隆
    标记
    • 12
    • 3
    • 2
    • 2
    • 2
    • 2
    • 1
    • 1
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    This SPAG1 antibody is un-conjugated
    应用范围
    • 21
    • 16
    • 15
    • 2
    • 1
    Western Blotting (WB), ELISA
    产品特性
    Polyclonal Antibody
    纯化方法
    Affinity purification
    免疫原
    Synthetic peptide of human SPAG1
    亚型
    IgG
    Top Product
    Discover our top product SPAG1 Primary Antibody
  • 应用备注
    WB 1:500-1:2000
    限制
    仅限研究用
  • 状态
    Liquid
    浓度
    0.3 mg/mL
    缓冲液
    PBS with 0.05 % sodium azide and 50 % glycerol, PH7.4
    储存液
    Sodium azide
    注意事项
    This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
    储存条件
    -20 °C
    储存方法
    Store at -20°C. Avoid freeze / thaw cycles.
  • 抗原
    SPAG1 (Sperm Associated Antigen 1 (SPAG1))
    别名
    SPAG1 (SPAG1 产品)
    别名
    cb1089 antibody, MGC162178 antibody, wu:fj78g10 antibody, sp75 antibody, tpis antibody, hsd-3.8 antibody, HSD-3.8 antibody, SP75 antibody, TPIS antibody, sperm associated antigen 1 antibody, sperm associated antigen 1a antibody, SPAG1 antibody, spag1a antibody, CpipJ_CPIJ006297 antibody, spag1 antibody, Spag1 antibody
    背景
    The correlation of anti-sperm antibodies with cases of unexplained infertility implicates a role for these antibodies in blocking fertilization. Improved diagnosis and treatment of immunologic infertility, as well as identification of proteins for targeted contraception, are dependent on the identification and characterization of relevant sperm antigens. The protein expressed by this gene is recognized by anti-sperm agglutinating antibodies from an infertile woman. Furthermore, immunization of female rats with the recombinant human protein reduced fertility. This protein localizes to the plasma membrane of germ cells in the testis and to the post-acrosomal plasma membrane of mature spermatozoa. Recombinant polypeptide binds GTP and exhibits GTPase activity. Thus, this protein may regulate GTP signal transduction pathways involved in spermatogenesis and fertilization. Two transcript variants of this gene encode the same protein.
    分子量
    104 kDa
    NCBI登录号
    NP_003105
    UniProt
    Q07617
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