C2orf12 antibody, HCC-4 antibody, MSSP antibody, MSSP-1 antibody, MSSP-2 antibody, MSSP-3 antibody, SCR2 antibody, YC1 antibody, 2600014B10Rik antibody, AI255215 antibody, RBMS1 antibody, fe16a10 antibody, wu:fe16a10 antibody, RNA binding motif single stranded interacting protein 1 antibody, RNA binding motif, single stranded interacting protein 1 antibody, RNA binding motif, single stranded interacting protein 1 S homeolog antibody, RNA binding motif, single stranded interacting protein 1a antibody, RBMS1 antibody, Rbms1 antibody, rbms1.S antibody, rbms1 antibody, rbms1a antibody
背景
His gene encodes a member of a small family of proteins which bind single stranded DNA/RNA. These proteins are characterized by the presence of two sets of ribonucleoprotein consensus sequence (RNP-CS) that contain conserved motifs, RNP1 and RNP2, originally described in RNA binding proteins, and required for DNA binding. These proteins have been implicated in such diverse functions as DNA replication, gene transcription, cell cycle progression and apoptosis. Several transcript variants, resulting from alternative splicing and encoding different isoforms, have been described. A pseudogene for this locus is found on chromosome 12.