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PDX1 抗体
PDX1
适用: 人, 小鼠, 大鼠
WB, ELISA, IHC
宿主: 兔
Polyclonal
unconjugated
PDX1抗体详情
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抗原
See all PDX1 抗体
PDX1
(Pancreatic and Duodenal Homeobox 1 (PDX1))
适用
All reactivities for PDX1 抗体
人, 小鼠, 大鼠
宿主
All hosts for PDX1 抗体
兔
克隆类型
All clonalities for PDX1 抗体
多克隆
标记
All conjugates for PDX1 抗体
This PDX1 antibody is un-conjugated
应用范围
All applications for PDX1 抗体
Western Blotting (WB), ELISA, Immunohistochemistry (IHC)
产品特性
Polyclonal Antibody
纯化方法
Affinity purification
免疫原
Synthetic peptide of human PDX1
亚型
IgG
Top Product
Discover our top product PDX1 Primary Antibody
Alternatives
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使用细节
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应用备注
WB 1:500-1:2000, IHC 1:15-1:50
限制
仅限研究用
贮存及处理
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状态
Liquid
浓度
0.4 mg/mL
缓冲液
PBS with 0.05 % sodium azide and 50 % glycerol, PH7.4
储存液
Sodium azide
注意事项
This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
储存条件
-20 °C
储存方法
Store at -20°C. Avoid freeze / thaw cycles.
PDX1目标详情
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抗原
PDX1
(Pancreatic and Duodenal Homeobox 1 (PDX1))
别名
PDX1 (PDX1 产品 )
别名
GSF antibody, IDX-1 antibody, IPF1 antibody, IUF1 antibody, MODY4 antibody, PDX-1 antibody, STF-1 antibody, ipf1 antibody, PDX1 antibody, IPF-1 antibody, Ipf1 antibody, Mody4 antibody, pdx-1 antibody, Idx1 antibody, Stf1 antibody, zgc:100874 antibody, XlHbox-8 antibody, xlhbox8 antibody, pancreatic and duodenal homeobox 1 antibody, pancreatic and duodenal homeobox 1 S homeolog antibody, PDX1 antibody, pdx1 antibody, Pdx1 antibody, pdx1.S antibody
背景
The protein encoded by this gene is a transcriptional activator of several genes, including insulin, somatostatin, glucokinase, islet amyloid polypeptide, and glucose transporter type 2. The encoded nuclear protein is involved in the early development of the pancreas and plays a major role in glucose-dependent regulation of insulin gene expression. Defects in this gene are a cause of pancreatic agenesis, which can lead to early-onset insulin-dependent diabetes mellitus (NIDDM), as well as maturity onset diabetes of the young type 4 (MODY4).
分子量
31 kDa
NCBI登录号
NP_000200
UniProt
P52945
途径
Nuclear Receptor Transcription Pathway , Positive Regulation of Peptide Hormone Secretion , Steroid Hormone Mediated Signaling Pathway , Hormone Transport , Carbohydrate Homeostasis , Chromatin Binding , Maintenance of Protein Location
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