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ABI1 抗体

ABI1 适用: 人, 大鼠, 小鼠 WB, ELISA, IHC 宿主: 兔 Polyclonal unconjugated
产品编号 ABIN7241930
发货至: 中国
  • 抗原 See all ABI1 抗体
    ABI1 (Abl-Interactor 1 (ABI1))
    适用
    • 49
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    人, 大鼠, 小鼠
    宿主
    • 63
    • 3
    克隆类型
    • 63
    • 3
    多克隆
    标记
    • 43
    • 2
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    • 1
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    • 1
    • 1
    • 1
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    This ABI1 antibody is un-conjugated
    应用范围
    • 54
    • 17
    • 16
    • 15
    • 14
    • 13
    • 13
    • 7
    • 6
    • 5
    • 4
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    Western Blotting (WB), ELISA, Immunohistochemistry (IHC)
    产品特性
    Polyclonal Antibody
    纯化方法
    Affinity purification
    免疫原
    Synthetic peptide of human ABI1
    亚型
    IgG
    Top Product
    Discover our top product ABI1 Primary Antibody
  • 应用备注
    WB 1:500-1:2000, IHC 1:50-1:200
    限制
    仅限研究用
  • 状态
    Liquid
    浓度
    0.6 mg/mL
    缓冲液
    PBS with 0.05 % sodium azide and 50 % glycerol, PH7.4
    储存液
    Sodium azide
    注意事项
    This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
    储存条件
    -20 °C
    储存方法
    Store at -20°C. Avoid freeze / thaw cycles.
  • 抗原
    ABI1 (Abl-Interactor 1 (ABI1))
    别名
    ABI1 (ABI1 产品)
    背景
    This gene encodes a member of the Abelson-interactor family of adaptor proteins. These proteins facilitate signal transduction as components of several multiprotein complexes, and regulate actin polymerization and cytoskeletal remodeling through interactions with Abelson tyrosine kinases. The encoded protein plays a role in macropinocytosis as a component of the WAVE2 complex, and also forms a complex with EPS8 and SOS1 that mediates signal transduction from Ras to Rac. This gene may play a role in the progression of several malignancies including melanoma, colon cancer and breast cancer, and a t(10,11) chromosomal translocation involving this gene and the MLL gene has been associated with acute myeloid leukemia. Alternatively spliced transcript variants encoding multiple isoforms have been observed for this gene, and a pseudogene of this gene is located on the long arm of chromosome 14
    分子量
    55 kDa
    NCBI登录号
    NP_005461
    UniProt
    Q8IZP0
    途径
    RTK signaling, Response to Water Deprivation, ER-Nucleus Signaling
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