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- 抗原 See all CPSF4 抗体
- CPSF4 (Cleavage and Polyadenylation Specific Factor 4, 30kDa (CPSF4))
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适用
- 人, 小鼠, 大鼠
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宿主
- 兔
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克隆类型
- 多克隆
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标记
- This CPSF4 antibody is un-conjugated
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应用范围
- Western Blotting (WB), ELISA
- 产品特性
- Polyclonal Antibody
- 纯化方法
- Affinity purification
- 免疫原
- Recombinant protein of human CPSF4
- 亚型
- IgG
- Top Product
- Discover our top product CPSF4 Primary Antibody
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anti-Cleavage and Polyadenylation Specific Factor 4, 30kDa (CPSF4) (AA 1-244) antibody
CPSF4 适用: 人 WB, ELISA, IHC 宿主: 兔 Polyclonal unconjugated
anti-Cleavage and Polyadenylation Specific Factor 4, 30kDa (CPSF4) (AA 81-180) antibodyCPSF4 适用: 人, 小鼠 WB, ELISA, IHC (fro), IHC (p) 宿主: 兔 Polyclonal unconjugated
anti-Cleavage and Polyadenylation Specific Factor 4, 30kDa (CPSF4) (C-Term) antibodyCPSF4 适用: 人, 小鼠 WB, IHC 宿主: 兔 Polyclonal unconjugated
anti-Cleavage and Polyadenylation Specific Factor 4, 30kDa (CPSF4) (AA 1-243) antibodyCPSF4 适用: 人 WB 宿主: 小鼠 Polyclonal unconjugated
anti-Cleavage and Polyadenylation Specific Factor 4, 30kDa (CPSF4) (C-Term) antibodyCPSF4 适用: 人, 小鼠, 大鼠, 犬, 豚鼠, 马, Pig, Bat, 猴 WB 宿主: 兔 Polyclonal unconjugated
anti-Cleavage and Polyadenylation Specific Factor 4, 30kDa (CPSF4) (AA 31-216) antibodyCPSF4 适用: 人 WB 宿主: 兔 Polyclonal unconjugated
anti-Cleavage and Polyadenylation Specific Factor 4, 30kDa (CPSF4) (C-Term) antibodyCPSF4 适用: 人, 小鼠, 大鼠, 犬 WB 宿主: 兔 Polyclonal unconjugated
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- 应用备注
- WB 1:500-1:2000
- 限制
- 仅限研究用
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- 状态
- Liquid
- 浓度
- 0.4 mg/mL
- 缓冲液
- PBS with 0.05 % sodium azide and 50 % glycerol, PH7.4
- 储存液
- Sodium azide
- 注意事项
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
- 储存条件
- -20 °C
- 储存方法
- Store at -20°C. Avoid freeze / thaw cycles.
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- 抗原
- CPSF4 (Cleavage and Polyadenylation Specific Factor 4, 30kDa (CPSF4))
- 别名
- CPSF4 (CPSF4 产品)
- 别名
- cpsf30 antibody, nar antibody, neb1 antibody, 30kDa antibody, C79664 antibody, CPSF30 antibody, NAR antibody, NEB1 antibody, cleavage and polyadenylation specific factor 4 antibody, cleavage and polyadenylation specific factor 4, 30kDa antibody, cleavage and polyadenylation specific factor 4 S homeolog antibody, CPSF4 antibody, Cpsf4 antibody, LOC733099 antibody, LOC100360200 antibody, cpsf4.S antibody, cpsf4 antibody
- 背景
- Inhibition of the nuclear export of poly(A)-containing mRNAs caused by the influenza A virus NS1 protein requires its effector domain. The NS1 effector domain functionally interacts with the cellular 30 kDa subunit of cleavage and polyadenylation specific factor 4, an essential component of the 3' end processing machinery of cellular pre-mRNAs. In influenza virus-infected cells, the NS1 protein is physically associated with cleavage and polyadenylation specific factor 4, 30kD subunit. Binding of the NS1 protein to the 30 kDa protein in vitro prevents CPSF binding to the RNA substrate and inhibits 3' end cleavage and polyadenylation of host pre-mRNAs. Thus the NS1 protein selectively inhibits the nuclear export of cellular, and not viral, mRNAs. Multiple alternatively spliced transcript variants that encode different isoforms have been described for this gene.
- 分子量
- 30 kDa
- UniProt
- O95639
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