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VWA5A 抗体

VWA5A 适用: 人 WB, ELISA, IHC 宿主: 兔 Polyclonal unconjugated
产品编号 ABIN7240895
发货至: 中国
  • 抗原 See all VWA5A 抗体
    VWA5A (Von Willebrand Factor A Domain Containing 5A (VWA5A))
    适用
    • 30
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    宿主
    • 23
    • 8
    克隆类型
    • 26
    • 5
    多克隆
    标记
    • 21
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    • 1
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    This VWA5A antibody is un-conjugated
    应用范围
    • 20
    • 9
    • 8
    • 4
    • 2
    • 2
    • 2
    • 1
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    Western Blotting (WB), ELISA, Immunohistochemistry (IHC)
    产品特性
    Polyclonal Antibody
    纯化方法
    Affinity purification
    免疫原
    Recombinant protein of human VWA5A
    亚型
    IgG
  • 应用备注
    WB 1:500-1:2000, IHC 1:100-1:300
    限制
    仅限研究用
  • 状态
    Liquid
    浓度
    0.5 mg/mL
    缓冲液
    PBS with 0.05 % sodium azide and 50 % glycerol, PH7.4
    储存液
    Sodium azide
    注意事项
    This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
    储存条件
    -20 °C
    储存方法
    Store at -20°C. Avoid freeze / thaw cycles.
  • 抗原
    VWA5A (Von Willebrand Factor A Domain Containing 5A (VWA5A))
    别名
    VWA5A (VWA5A 产品)
    别名
    VWA5A antibody, LOH11CR2A antibody, MGC68953 antibody, loh11cr2a antibody, BCSC-1 antibody, BCSC1 antibody, 5830475I06Rik antibody, AW552491 antibody, E130119J22 antibody, Loh11cr2a antibody, masa-1 antibody, loss of heterozygosity, 11, chromosomal region 2, gene A antibody, von Willebrand factor A domain containing 5A antibody, von Willebrand factor A domain containing 5A S homeolog antibody, LOH11CR2A antibody, VWA5A antibody, vwa5a.S antibody, vwa5a antibody, Vwa5a antibody
    背景
    VWA5A (von Willebrand factor A domain containing 5A), also known as BCSC-1 (breast cancer suppressor candidate 1) or LOH11CR2A (loss of heterozygosity 11 chromosomal region 2 gene A protein), is a 786 amino acid protein containing one VIT domain and one VWFA domain. VWA5A is expressed at low levels in various tissues, with no expression found in 80 % of tumor cell lines. Likely acting as a tumor suppressor gene, deletion of VWA5A leads to loss of heterozygosity (LOH) in breast and ovarian tumors, and may have an important role as a potential gene therapy target. Abnormal expression of VWA5A may lead to an increase in adhesion of CNE-2L2 cells associated with an increase in expression of E-cadherin, alpha-catenin, and p53, resulting in a decrease of malignant activity in cells with ectopic expression of VWA5A.
    分子量
    86 kDa
    UniProt
    O00534
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