acsl4 antibody, zgc:66186 antibody, ACSL4 antibody, ACS4 antibody, FACL4 antibody, LACS4 antibody, MRX63 antibody, MRX68 antibody, 9430020A05Rik antibody, AU018108 antibody, Facl4 antibody, Lacs4 antibody, Acs4 antibody, acs4 antibody, acsl3 antibody, facl4 antibody, lacs4 antibody, mrx63 antibody, mrx68 antibody, T32A16.20 antibody, T32A16_20 antibody, long-chain acyl-CoA synthetase 4 antibody, acyl-CoA synthetase long chain family member 4a antibody, acyl-CoA synthetase long-chain family member 4 antibody, acyl-CoA synthetase long chain family member 4 antibody, AcsL4 antibody, acyl-CoA synthetase long chain family member 3 antibody, Long-chain-fatty-acid--CoA ligase 4 antibody, acyl-CoA synthetase long-chain family member 4 S homeolog antibody, AMP-dependent synthetase and ligase family protein antibody, acsl4a antibody, ACSL4 antibody, acsL4 antibody, acsl3 antibody, acsl4 antibody, Acsl4 antibody, acsl4.S antibody, LACS4 antibody
背景
The protein encoded by this gene is an isozyme of the long-chain fatty-acid-coenzyme A ligase family. Although differing in substrate specificity, subcellular localization, and tissue distribution, all isozymes of this family convert free long-chain fatty acids into fatty acyl-CoA esters, and thereby play a key role in lipid biosynthesis and fatty acid degradation. This isozyme preferentially utilizes arachidonate as substrate. The absence of this enzyme may contribute to the mental retardation or Alport syndrome. Alternative splicing of this gene generates 2 transcript variants.