Met antibody, 5730455C01Rik antibody, 5730555F13Rik antibody, 9130215G10Rik antibody, SAFB like transcription modulator antibody, SAFB-like, transcription modulator antibody, SAFB-like, transcription modulator S homeolog antibody, SLTM antibody, Sltm antibody, sltm.S antibody
背景
SLTM (SAFB-like, transcription modulator), also known as MET (modulator of estrogen-induced transcription), is a 1,034 amino acid protein that localizes to punctate structures within the nucleus and contains one SAP domain and one RNA recognition motif. When expressed at high levels, SLTM functions to inhibit transcription and may, ultimately, lead to apoptosis. Multiple isoforms of SLTM exist due to alternative splicing events. The gene encoding SLTM maps to human chromosome 15, which houses over 700 genes and comprises nearly 3 % of the human genome.