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- 抗原 See all HIF1AN 抗体
- HIF1AN (Hypoxia Inducible Factor 1, alpha Subunit Inhibitor (HIF1AN))
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适用
- 人, 小鼠
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宿主
- 兔
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克隆类型
- 多克隆
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标记
- This HIF1AN antibody is un-conjugated
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应用范围
- Western Blotting (WB), ELISA, Immunohistochemistry (IHC)
- 产品特性
- Polyclonal Antibody
- 纯化方法
- Affinity purification
- 免疫原
- Synthetic peptide of human HIF1AN
- 亚型
- IgG
- Top Product
- Discover our top product HIF1AN Primary Antibody
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anti-Hypoxia Inducible Factor 1, alpha Subunit Inhibitor (HIF1AN) (AA 31-349) antibody
HIF1AN 适用: 人 WB, IHC, IP, ICC 宿主: 兔 Polyclonal unconjugated
anti-Hypoxia Inducible Factor 1, alpha Subunit Inhibitor (HIF1AN) (AA 1-349) antibodyHIF1AN 适用: 人 WB, ELISA, IP, IF 宿主: 小鼠 Monoclonal 1D8 unconjugated
anti-Hypoxia Inducible Factor 1, alpha Subunit Inhibitor (HIF1AN) (AA 2-254) antibodyHIF1AN 适用: 人 WB, ELISA, IHC, IP, IF 宿主: 兔 Polyclonal unconjugated
anti-Hypoxia Inducible Factor 1, alpha Subunit Inhibitor (HIF1AN) (AA 1-349) antibodyHIF1AN 适用: 人 WB, IP, IF 宿主: 兔 Polyclonal unconjugated
anti-Hypoxia Inducible Factor 1, alpha Subunit Inhibitor (HIF1AN) (N-Term) antibodyHIF1AN 适用: 人, 兔, 马 WB, IHC, IHC (p) 宿主: 兔 Polyclonal unconjugated
anti-Hypoxia Inducible Factor 1, alpha Subunit Inhibitor (HIF1AN) (AA 1-349) antibodyHIF1AN 适用: 人 WB, IF 宿主: 小鼠 Monoclonal 931CT3-1-1 unconjugated
anti-Hypoxia Inducible Factor 1, alpha Subunit Inhibitor (HIF1AN) (C-Term) antibodyHIF1AN 适用: 人, 小鼠, 大鼠 WB, ELISA, IHC 宿主: 兔 Polyclonal unconjugated
anti-Hypoxia Inducible Factor 1, alpha Subunit Inhibitor (HIF1AN) antibodyHIF1AN 适用: 人, 小鼠, 大鼠 WB, IHC, IP, IF, ChIP, IC 宿主: 兔 Polyclonal unconjugated
anti-Hypoxia Inducible Factor 1, alpha Subunit Inhibitor (HIF1AN) (AA 1-349) antibodyHIF1AN 适用: 人 WB, ELISA 宿主: 小鼠 Polyclonal unconjugated
anti-Hypoxia Inducible Factor 1, alpha Subunit Inhibitor (HIF1AN) (AA 183-232) antibodyHIF1AN 适用: 人, 小鼠, 大鼠, 兔, 犬, 马, Cow, 豚鼠, 斑马鱼, Pig, 猴, 小鸡, 非洲爪蟾, Bat WB 宿主: 兔 Polyclonal unconjugated
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- 应用备注
- WB 1:500-1:2000, IHC 1:50-1:300
- 限制
- 仅限研究用
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- 状态
- Liquid
- 浓度
- 0.6 mg/mL
- 缓冲液
- PBS with 0.05 % sodium azide and 50 % glycerol, PH7.4
- 储存液
- Sodium azide
- 注意事项
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
- 储存条件
- -20 °C
- 储存方法
- Store at -20°C. Avoid freeze / thaw cycles.
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- 抗原
- HIF1AN (Hypoxia Inducible Factor 1, alpha Subunit Inhibitor (HIF1AN))
- 别名
- HIF1AN (HIF1AN 产品)
- 别名
- FIH1 antibody, 2310046M24Rik antibody, A830014H24Rik antibody, cb728 antibody, id:ibd5139 antibody, hypoxia inducible factor 1 alpha subunit inhibitor antibody, hypoxia-inducible factor 1, alpha subunit inhibitor antibody, hypoxia inducible factor 1, alpha subunit inhibitor antibody, hypoxia-inducible factor 1, alpha subunit inhibitor S homeolog antibody, HIF1AN antibody, Hif1an antibody, hif1an antibody, hif1an.S antibody
- 背景
- Factor inhibiting HIF-1 (FIH-1) exists as a homodimer and binds to HIF-1alpha. Specifically, FIH-1 operates as an asparaginyl hydroxylase. It catalyzes the hydroxylation of the beta-carbon of Asparagine residue 803 within the carboxy terminal transactivation domain of HIF-1alpha. This hydroxylation event blocks the association of HIF-1alpha with co-activators. FIH-1 also binds to von Hippel-Lindau (VHL) tumor suppressor protein, which represses transcriptional ac-tivity of HIF-1alpha. In transiently transfected human osteosarcoma cells, FIH-1 localizes to the cytoplasm.
- 分子量
- 40 kDa
- NCBI登录号
- NP_060372
- UniProt
- Q9NWT6
- 途径
- Regulation of Muscle Cell Differentiation, Skeletal Muscle Fiber Development
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