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CAB39 抗体

CAB39 适用: 人, 小鼠 WB, ELISA, IHC 宿主: 兔 Polyclonal unconjugated
产品编号 ABIN7239215
发货至: 中国
  • 抗原 See all CAB39 抗体
    CAB39 (Calcium Binding Protein 39 (CAB39))
    适用
    • 37
    • 7
    • 3
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    人, 小鼠
    宿主
    • 35
    • 4
    克隆类型
    • 37
    • 2
    多克隆
    标记
    • 14
    • 3
    • 3
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    This CAB39 antibody is un-conjugated
    应用范围
    • 29
    • 13
    • 13
    • 9
    • 4
    • 3
    • 2
    • 1
    • 1
    • 1
    Western Blotting (WB), ELISA, Immunohistochemistry (IHC)
    产品特性
    Polyclonal Antibody
    纯化方法
    Affinity purification
    免疫原
    Synthetic peptide of human CAB39
    亚型
    IgG
  • 应用备注
    WB 1:500-1:2000, IHC 1:50-1:200
    限制
    仅限研究用
  • 状态
    Liquid
    浓度
    1.7 mg/mL
    缓冲液
    PBS with 0.05 % sodium azide and 50 % glycerol, PH7.4
    储存液
    Sodium azide
    注意事项
    This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
    储存条件
    -20 °C
    储存方法
    Store at -20°C. Avoid freeze / thaw cycles.
  • 抗原
    CAB39 (Calcium Binding Protein 39 (CAB39))
    别名
    CAB39 (CAB39 产品)
    别名
    CG4083 antibody, Dmel\\CG4083 antibody, Dmo25 antibody, dMo25 antibody, l(3)00274 antibody, mo25 antibody, fc06a03 antibody, zgc:86716 antibody, wu:fc06a03 antibody, MGC78903 antibody, CAB39 antibody, MO25 antibody, AA408805 antibody, AA960512 antibody, C78372 antibody, MO25alpha antibody, CG4083 gene product from transcript CG4083-RA antibody, calcium binding protein 39 antibody, calcium binding protein 39 L homeolog antibody, Cab39 protein antibody, Mo25 antibody, cab39 antibody, cab39.L antibody, CAB39 antibody, Bm1_33380 antibody, Cab39 antibody
    背景
    Peutz-Jeghers Syndrome (PJS) is a rare hereditary disease characterized by melanocytic macules of the lips, gastrointestinal hamartomatous polyps and an increased risk for many classes of cancer. The serine/threonine kinase LKB1 (also designated STK11) has been identified as the gene mutated in PJS. LKB1 activity increases upon the binding of a regulatory complex consisting of the STE20-related adaptor-alpha (STRAD alpha) pseudo kinase and the calcium binding protein 39 (MO25 alpha). STRAD and MO25 determine the subcellular localization of LKB1 by initiating its translocation from the nucleus to the cytoplasm, thus regulating the tumor suppressor activity of LKB1. The LKB1/STRAD/MO25 complex acts as an AMP-activated protein kinase kinase (AMPKK).
    分子量
    40 kDa
    NCBI登录号
    NP_057373
    UniProt
    Q9Y376
    途径
    AMPK Signaling
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