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HMGCS1 抗体

HMGCS1 适用: 人 WB, ELISA, IHC 宿主: 兔 Polyclonal unconjugated
产品编号 ABIN7239032
发货至: 中国
  • 抗原 See all HMGCS1 抗体
    HMGCS1 (3-Hydroxy-3-Methylglutaryl-CoA Synthase 1 (Soluble) (HMGCS1))
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    克隆类型
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    多克隆
    标记
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    This HMGCS1 antibody is un-conjugated
    应用范围
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    Western Blotting (WB), ELISA, Immunohistochemistry (IHC)
    产品特性
    Polyclonal Antibody
    纯化方法
    Affinity purification
    免疫原
    Synthetic peptide of human HMGCS1
    亚型
    IgG
    Top Product
    Discover our top product HMGCS1 Primary Antibody
  • 应用备注
    WB 1:500-1:2000, IHC 1:50-1:200
    限制
    仅限研究用
  • 状态
    Liquid
    浓度
    0.4 mg/mL
    缓冲液
    PBS with 0.05 % sodium azide and 50 % glycerol, PH7.4
    储存液
    Sodium azide
    注意事项
    This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
    储存条件
    -20 °C
    储存方法
    Store at -20°C. Avoid freeze / thaw cycles.
  • 抗原
    HMGCS1 (3-Hydroxy-3-Methylglutaryl-CoA Synthase 1 (Soluble) (HMGCS1))
    别名
    HMGCS1 (HMGCS1 产品)
    别名
    HMGCS antibody, zgc:56481 antibody, B130032C06Rik antibody, 3-hydroxy-3-methylglutaryl-CoA synthase 1 antibody, 3-hydroxy-3-methylglutaryl-CoA synthase 1 (soluble) antibody, 3-hydroxy-3-methylglutaryl-Coenzyme A synthase 1 antibody, 3-hydroxy-3-methylglutaryl coenzyme A synthase antibody, hydroxymethylglutaryl-CoA synthase antibody, 3-hydroxy-3-methylglutaryl-CoA synthase antibody, hydroxymethylglutaryl coenzyme A synthase antibody, 3-hydroxy-3-methylglutaryl-CoA synthase 1 S homeolog antibody, HMGCS1 antibody, hmgcs1 antibody, Hmgcs1 antibody, mvaS antibody, SAS2432 antibody, SZO_RS04705 antibody, SEQ_1109 antibody, NAEGRDRAFT_77778 antibody, hmgcs1.S antibody
    背景
    HMG-CoA Synthase exists as both a mitochondrial (mHMGCS) and cytoplasmic (cHMGCS) enzyme that condenses acetyl-CoA with acetoacetyl-CoA to form HMG-CoA. The HMG-CoA produced by cHMGCS is transformed into mevalonate by HMG-CoA reductase, which starts isoprenoid biosynthesis. End products of the isoprenoid pathway include cholesterol, ubiquinone, dolichol, isopentenyl adenosine and farnesyl groups. mHMGCS, together with HMG-CoA Lyase, is responsible for ketone body biosynthesis. mHMGCS is expressed in liver and kidney. Fasting, cAMP and fatty acids increase the level of transcription of mHMGCS, while feeding and insulin repress it. A regulatory element within the mHMGCS promoter confers transcriptional regulation by PPAR, RXR, COUP-TF and HNF-4.
    分子量
    57 kDa
    NCBI登录号
    NP_001091742
    UniProt
    Q01581
    途径
    Regulation of Lipid Metabolism by PPARalpha
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