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NUAK1 抗体

NUAK1 适用: 人, 小鼠 ELISA, IHC 宿主: 兔 Polyclonal unconjugated
产品编号 ABIN7238549
发货至: 中国
  • 抗原 See all NUAK1 抗体
    NUAK1 (NUAK Family, SNF1-Like Kinase, 1 (NUAK1))
    适用
    • 56
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    人, 小鼠
    宿主
    • 52
    • 4
    • 1
    克隆类型
    • 56
    • 1
    多克隆
    标记
    • 22
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    This NUAK1 antibody is un-conjugated
    应用范围
    • 28
    • 24
    • 17
    • 13
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    • 6
    • 3
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    • 2
    • 1
    • 1
    ELISA, Immunohistochemistry (IHC)
    产品特性
    Polyclonal Antibody
    纯化方法
    Affinity purification
    免疫原
    Synthetic peptide of human NUAK1
    亚型
    IgG
    Top Product
    Discover our top product NUAK1 Primary Antibody
  • 应用备注
    IHC 1:25-1:100
    限制
    仅限研究用
  • 状态
    Liquid
    浓度
    0.6 mg/mL
    缓冲液
    PBS with 0.05 % sodium azide and 50 % glycerol, PH7.4
    储存液
    Sodium azide
    注意事项
    This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
    储存条件
    -20 °C
    储存方法
    Store at -20°C. Avoid freeze / thaw cycles.
  • 抗原
    NUAK1 (NUAK Family, SNF1-Like Kinase, 1 (NUAK1))
    别名
    NUAK1 (NUAK1 产品)
    别名
    ARK5 antibody, AU014801 antibody, AW494241 antibody, B230104P22Rik antibody, Omphk1 antibody, NUAK family kinase 1 antibody, NUAK family, SNF1-like kinase, 1 antibody, NUAK1 antibody, Nuak1 antibody
    背景
    NUAK family SNF1-like kinase 1also known asAMPK-related protein kinase 5(ARK5) is anenzymethat in humans is encoded by theNUAK1gene. Serine/threonine-protein kinase involved in various processes such as cell adhesion, regulation of cell ploidy and senescence, cell proliferation and tumor progression. Phosphorylates ATM, CASP6, LATS1, PPP1R12A and p53/TP53. Acts as a regulator of cellular senescence and cellular ploidy by mediating phosphorylation of 'Ser-464' of LATS1, thereby controlling its stability. Controls cell adhesion by regulating activity of the myosin protein phosphatase 1 (PP1) complex. Acts by mediating phosphorylation of PPP1R12A subunit of myosin PP1: phosphorylated PPP1R12A then interacts with 14-3-3, leading to reduced dephosphorylation of myosin MLC2 by myosin PP1.
    NCBI登录号
    NP_055655
    UniProt
    O60285
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