SLC8A3 antibody, NCX3 antibody, Ncx3 antibody, AW742262 antibody, solute carrier family 8 member A3 antibody, solute carrier family 8 (sodium/calcium exchanger), member 3 antibody, SLC8A3 antibody, slc8a3 antibody, Slc8a3 antibody
背景
This gene encodes a member of the sodium/calcium exchanger integral membrane protein family. Three mammalian isoforms in family 8 have been identified. Na+/Ca2+ exchange proteins are involved in maintaining Ca2+ homeostasis in a wide variety of cell types. The protein is regulated by intracellular calcium ions and is found in both the plasma membrane and intracellular organellar membranes, where exchange of Na+ for Ca2+ occurs in an electrogenic manner. Alternative splicing has been observed for this gene and multiple variants have been described.