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SMG8 抗体
SMG8
适用: 人, 小鼠
IHC, ELISA
宿主: 兔
Polyclonal
unconjugated
SMG8抗体详情
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抗原
See all SMG8 抗体
SMG8
(Smg-8 Homolog, Nonsense Mediated mRNA Decay Factor (SMG8))
适用
All reactivities for SMG8 抗体
人, 小鼠
宿主
All hosts for SMG8 抗体
兔
克隆类型
All clonalities for SMG8 抗体
多克隆
标记
All conjugates for SMG8 抗体
This SMG8 antibody is un-conjugated
应用范围
All applications for SMG8 抗体
Immunohistochemistry (IHC), ELISA
产品特性
Polyclonal Antibody
纯化方法
Affinity purification
免疫原
Synthetic peptide of human SMG8
亚型
IgG
Alternatives
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anti-Smg-8 Homolog, Nonsense Mediated mRNA Decay Factor (SMG8) (AA 575-624) antibody
SMG8
适用: 人, 小鼠, Cow, 马, 兔, Pig, 大鼠, 犬, 豚鼠, Bat, 猴
WB
宿主: 兔
Polyclonal
unconjugated
使用细节
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应用备注
IHC 1:25-1:100
限制
仅限研究用
贮存及处理
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状态
Liquid
浓度
0.3 mg/mL
缓冲液
PBS with 0.05 % sodium azide and 50 % glycerol, PH7.4
储存液
Sodium azide
注意事项
This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
储存条件
-20 °C
储存方法
Store at -20°C. Avoid freeze / thaw cycles.
SMG8目标详情
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抗原
SMG8
(Smg-8 Homolog, Nonsense Mediated mRNA Decay Factor (SMG8))
别名
SMG8 (SMG8 产品 )
别名
C17orf71 antibody, 1200011M11Rik antibody, C19H17orf71 antibody, SMG8, nonsense mediated mRNA decay factor antibody, smg-8 homolog, nonsense mediated mRNA decay factor (C. elegans) antibody, Protein smg-8 antibody, SMG8 antibody, Smg8 antibody, smg-8 antibody
背景
Involved in nonsense-mediated decay (NMD) of mRNAs containing premature stop codons. Is recruited by release factors to stalled ribosomes together with SMG1 and SMG9 (forming the SMG1C protein kinase complex) and, in the SMG1C complex, is required to mediate the recruitment of SMG1 to the ribosome:SURF complex and to suppress SMG1 kinase activity until the ribosome:SURF complex locates the exon junction complex (EJC). Acts as a regulator of kinase activity.
NCBI登录号
NP_060619
UniProt
Q8ND04
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