E2F4 抗体
-
- 抗原 See all E2F4 抗体
- E2F4 (E2F Transcription Factor 4, P107/p130-Binding (E2F4))
-
适用
- 人, 小鼠
-
宿主
- 兔
-
克隆类型
- 多克隆
-
标记
- This E2F4 antibody is un-conjugated
-
应用范围
- ELISA, Immunohistochemistry (IHC)
- 产品特性
- Polyclonal Antibody
- 纯化方法
- Affinity purification
- 免疫原
- Synthetic peptide of human E2F4
- 亚型
- IgG
- Top Product
- Discover our top product E2F4 Primary Antibody
-
-
- 应用备注
- IHC 1:50-1:200
- 限制
- 仅限研究用
-
- 状态
- Liquid
- 浓度
- 0.5 mg/mL
- 缓冲液
- PBS with 0.05 % sodium azide and 50 % glycerol, PH7.4
- 储存液
- Sodium azide
- 注意事项
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
- 储存条件
- -20 °C
- 储存方法
- Store at -20°C. Avoid freeze / thaw cycles.
-
- 抗原
- E2F4 (E2F Transcription Factor 4, P107/p130-Binding (E2F4))
- 别名
- E2F4 (E2F4 产品)
- 背景
- The protein encoded by this gene is a member of the E2F family of transcription factors. The E2F family plays a crucial role in the control of cell cycle and action of tumor suppressor proteins and is also a target of the transforming proteins of small DNA tumor viruses. The E2F proteins contain several evolutionally conserved domains found in most members of the family. These domains include a DNA binding domain, a dimerization domain which determines interaction with the differentiation regulated transcription factor proteins (DP), a transactivation domain enriched in acidic amino acids, and a tumor suppressor protein association domain which is embedded within the transactivation domain. This protein binds to all three of the tumor suppressor proteins pRB, p107 and p130, but with higher affinity to the last two.
- NCBI登录号
- NP_001941
- UniProt
- Q16254
- 途径
- Cell Division Cycle, Mitotic G1-G1/S Phases, Regulation of Cell Size
-