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Desmoplakin 抗体

DSP 适用: 人, 小鼠 IHC, ELISA 宿主: 兔 Polyclonal unconjugated
产品编号 ABIN7237973
发货至: 中国
  • 抗原 See all Desmoplakin (DSP) 抗体
    Desmoplakin (DSP)
    适用
    • 32
    • 14
    • 5
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    人, 小鼠
    宿主
    • 27
    • 3
    • 2
    • 1
    克隆类型
    • 30
    • 3
    多克隆
    标记
    • 22
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    This Desmoplakin antibody is un-conjugated
    应用范围
    • 15
    • 10
    • 9
    • 5
    • 4
    • 4
    • 2
    • 1
    • 1
    • 1
    • 1
    Immunohistochemistry (IHC), ELISA
    产品特性
    Polyclonal Antibody
    纯化方法
    Affinity purification
    免疫原
    Synthetic peptide of human DSP
    亚型
    IgG
    Top Product
    Discover our top product DSP Primary Antibody
  • 应用备注
    IHC 1:50-1:200
    限制
    仅限研究用
  • 状态
    Liquid
    浓度
    0.5 mg/mL
    缓冲液
    PBS with 0.05 % sodium azide and 50 % glycerol, PH7.4
    储存液
    Sodium azide
    注意事项
    This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
    储存条件
    -20 °C
    储存方法
    Store at -20°C. Avoid freeze / thaw cycles.
  • 抗原
    Desmoplakin (DSP)
    别名
    DSP (DSP 产品)
    背景
    Desmosomes are intercellular junctions that tightly link adjacent cells. Desmoplakin is an obligate component of functional desmosomes that anchors intermediate filaments to desmosomal plaques. The N-terminus of desmoplakin is required for localization to the desmosome and interacts with the N-terminal region of plakophilin 1 and plakoglobin. The C-terminus of desmoplakin binds with intermediate filaments. In the mid-region of desmoplakin, a coiled-coiled rod domain is responsible for homodimerization. Mutations in this gene are the cause of several cardiomyopathies and keratodermas as well as the autoimmune disease paraneoplastic pemphigus.
    NCBI登录号
    NP_004406
    UniProt
    P15924
    途径
    Cell-Cell Junction Organization
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