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CRELD2 抗体

CRELD2 适用: 人 WB, ELISA, IHC 宿主: 兔 Polyclonal unconjugated
产品编号 ABIN7236677
发货至: 中国
  • 抗原 See all CRELD2 抗体
    CRELD2 (Cysteine-Rich with EGF-Like Domains 2 (CRELD2))
    适用
    • 43
    • 17
    • 2
    • 2
    • 2
    • 1
    • 1
    • 1
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    宿主
    • 54
    • 4
    克隆类型
    • 57
    • 1
    多克隆
    标记
    • 17
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    • 4
    • 1
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    This CRELD2 antibody is un-conjugated
    应用范围
    • 50
    • 30
    • 14
    • 13
    • 13
    • 3
    • 3
    • 1
    Western Blotting (WB), ELISA, Immunohistochemistry (IHC)
    产品特性
    Polyclonal Antibody
    纯化方法
    Affinity purification
    免疫原
    Recombinant protein of human CRELD2
    亚型
    IgG
  • 应用备注
    WB 1:500-1:2000, IHC 1:50-1:200
    限制
    仅限研究用
  • 状态
    Liquid
    浓度
    0.3 mg/mL
    缓冲液
    PBS with 0.05 % sodium azide and 50 % glycerol, PH7.4
    储存液
    Sodium azide
    注意事项
    This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
    储存条件
    -20 °C
    储存方法
    Store at -20°C. Avoid freeze / thaw cycles.
  • 抗原
    CRELD2 (Cysteine-Rich with EGF-Like Domains 2 (CRELD2))
    别名
    CRELD2 (CRELD2 产品)
    别名
    zgc:66383 antibody, CRELD2 antibody, 5730592L21Rik antibody, C85758 antibody, RGD1310614 antibody, cysteine-rich with EGF-like domains 2 antibody, cysteine rich with EGF like domains 2 antibody, creld2 antibody, CRELD2 antibody, Creld2 antibody
    背景
    The epidermal growth factor (EGF) repeat-containing proteins constitute an expanding family of proteins that are involved in several cellular activities, such as blood coagulation, fibrinolysis, cell adhesion and neural and vertebrate development. CRELD2 (cysteine-rich with EGF-like domains 2) is a 353 amino acid protein that is ubiquitously expressed and contains two FU domains and two EGF-like domains. Localized to the endoplasmic reticulum and secreted into the cell, CRELD2 interacts with AChR4, possibly regulating its transport. Human CRELD2 shares 69 % amino acid identity with its mouse counterpart, suggesting a conserved role between species. Multiple isoforms of CRELD2 exist due to alternative splicing events. The gene encoding CRELD2 maps to human chromosome 22, which houses over 500 genes and is the second smallest human chromosome. Mutations in several of the genes that map to chromosome 22 are involved in the development of Phelan-McDermid syndrome, Neurofibromatosis type 2, autism and schizophrenia.
    分子量
    38 kDa
    UniProt
    Q6UXH1
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