CDR62 antibody, Yo antibody, cdr2 antibody, MGC69206 antibody, CDR2 antibody, AA617262 antibody, RGD1310578 antibody, cerebellar degeneration related protein 2 antibody, cerebellar degeneration related protein 2 L homeolog antibody, cerebellar degeneration-related 2 antibody, cerebellar degeneration-related protein 2 antibody, cerebellar degeneration related protein 2 like antibody, CDR2 antibody, cdr2 antibody, cdr2.L antibody, Cdr2 antibody, CDR2L antibody, LOC101060399 antibody
背景
CDR2 (cerebellar degeneration-related protein 2), also referred to as Yo or CDR62, is a 545 amino acid protein that is associated with the development of paraneoplastic cerebellar degeneration (PCD). PCD, an immune-mediated syndrome, belongs to a heterogeneous group of rare paraneoplastic neurologic disorders affecting the neurological system. PCD is characterized by subacute cerebellar ataxia and occurs mainly in patients with ovarian, uterine, fallopian tube or breast cancer.