PROS antibody, PS21 antibody, PS22 antibody, PS23 antibody, PS24 antibody, PS25 antibody, PSA antibody, THPH5 antibody, THPH6 antibody, zgc:154001 antibody, AW214361 antibody, protein S antibody, protein S (alpha) antibody, PROS1 antibody, Pros1 antibody, pros1 antibody
背景
This gene encodes a vitamin K-dependent plasma protein that functions as a cofactor for the anticoagulant protease, activated protein C (APC) to inhibit blood coagulation. It is found in plasma in both a free, functionally active form and also in an inactive form complexed with C4b-binding protein. Mutations in this gene result in autosomal dominant hereditary thrombophilia. An inactive pseudogene of this locus is located at an adjacent region on chromosome 3.